Current Engineering Advances in Drug Delivery Systems Utilizing Silver Nanoparticles
- VernacularTitle:Эмийн хүргэлтийн системийн шинж чанарыг нано хэмжээст мөнгө ашиглан сайжруулах инженерчлэлийн өнөөгийн байдал
- Author:
Oldokh O
1
;
Altantogos M
1
;
2
;
Molomjamts B
1
;
Altansukh Ts
3
;
4
Author Information
1. Department of Medical Chemistry, School of Biomedicine, MNUMS
2. Department of Chemical and Biological engineering, School of Engineering and Technology, NUM
3. Graduate school of Medical Science, MNUMS
4. Department of Molecular Biology and Genetics, School of Biomedicine, MNUMS
- Publication Type:Review
- Keywords:
Silver;
Nanoparticles;
Drug delivery;
Targeted delivery;
Therapeutic activity
- From:
Mongolian Journal of Health Sciences
2026;92(2):196-200
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Over the past decade, silver nanoparticles (AgNPs) have gained considerable attention in biomedical research due to their unique physicochemical properties and intrinsic biological activity. Their nanoscale dimensions, high surface-to-volume ratio, and tunable surface chemistry make them promising candidates for advanced drug delivery applications. AgNP-based systems provide a versatile platform for controlled and site-specific drug release, thereby enhancing therapeutic efficacy while minimizing systemic side effects. This review article summarizes the properties of zeolites enhanced with silver nanoparticles (AgNPs). Drug delivery systems incorporating AgNPs operate through both passive and active targeting mechanisms to transport therapeutic agents, including antibiotics, anti-inflammatory drugs, and anticancer compounds, to specific tissues or pathological sites. The performance of these systems is largely governed by the physicochemical characteristics of AgNPs, such as particle size, morphology, surface charge, stability, and surface functionalization. Surface modification enables improved biocompatibility, enhanced drug loading capacity, and controlled release kinetics. Furthermore, the inherent antibacterial activity of AgNPs contributes synergistically to therapeutic outcomes, particularly in the treatment of infected wounds and biofilm-associated infections.
Materials and Methods:This review article was prepared by selecting and analyzing relevant publications indexed in Scopus and Web of Science published between 2005 and 2025, focusing on characteristics of AgNPs, drug delivery systems based on zeolites modified with AgNPs and their applications.
Conclusion:Silver nanoparticle-based drug delivery systems represent an advanced and multifunctional therapeutic platform. Their capacity for targeted, sustained, and controlled drug release, combined with intrinsic antimicrobial activity, offers significant advantages over conventional delivery systems. These properties position AgNPs as promising materials for the development of next-generation biomedical and pharmaceutical applications.
- Full text:202609272052466654537.pdf
