Clinical study of the anti-influenza effect of De-Mon syrup based on a traditional prescription
- VernacularTitle:Уламжлалт жор найрлагад суурилсан Дэ-Мон сиропын томуугийн эсрэг эмнэлзүйн судалгаа
- Author:
Munkhjargal J
1
;
Manaljav Ts
2
;
Altantuyaa Ts
3
;
Oyuntsetseg N
1
Author Information
1. Department of Traditional Therapy, School of Mongolian Traditional Medicine, MNUMS
2. Department of Pulmonology, School of Medicine, MNUMS
3. Department of Pediatrics, School of Medicine, MNUMS
- Publication Type:Journal Article
- Keywords:
Influenza;
Herbal syrup;
Antiviral therapy;
Traditional medicine;
Clinical study
- From:
Mongolian Journal of Health Sciences
2026;92(2):115-118
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Previous studies on Deva-5 traditional prescription, which has long been used in traditional medicine for the treatment of influenza, have demonstrated inhibitory activity against influenza A (H3) virus and antimicrobial activity against Staphylococcus aureus. Based on this traditional formula, De-Mon syrup was developed through pharmaceutical processing. Experimental studies have shown that this syrup possesses anti-inflammatory properties. Therefore, conducting a clinical study to evaluate its therapeutic effect in influenza is warranted.
Aim:To investigate the anti-inflammatory effect of De-Mon syrup, derived from a traditional herbal formulation, in patients with influenza.
Materials and Methods:A randomized controlled clinical trial with a parallel design was conducted among 160 patients diagnosed with influenza (ICD-10: J09–J11) who met the inclusion criteria. Participants were randomly assigned into two groups. The treatment group received standard influenza therapy with oseltamivir combined with De-Mon syrup, administered four times daily for five days at age-appropriate doses for children and adults. The control group received oseltamivir twice daily for five days. Complete blood count parameters were measured before and after treatment, and the results were statistically analyzed.
Result:According to the study results, the adult treatment group demonstrated a statistically significant reduction in white blood cell and neutrophil counts compared with the control group (p<0.05). Similarly, when children in the treatment group were compared with those in the control group, white blood cell count, C-reactive protein levels, and neutrophil counts were significantly decreased, indicating statistically significant differences (p<0.05).
Conclusion:De-mon syrup, based on a traditional prescription, significantly reduced white blood cell count, C-reactive protein, and neutrophil levels in patients with influenza (p<0.05), indicating a potential anti-inflammatory effect.
- Full text:202609262108298577421.pdf
