Familial cerebral cavernous malformations
- VernacularTitle:Тархины эдийн цус харвалтаар илэрсэн гэр бүлийн тархины каверномын ховор тохиолдол
- Author:
Dembereldorj S
1
;
Dungar-Yaichil S
2
;
Uurtsaikh G
3
;
Otgonbayar B
4
;
Altantsetseg Ts
5
;
Lkhamtsoo N
1
Author Information
1. Third State Central Hospital
2. Citymed Hospital
3. Intermed Hospital
4. Songinokhairkhan District Health Centre
5. Dornod Regional Diagnostic and Treatment Centre
- Publication Type:Case Reports
- Keywords:
Genetic factors;
Clinical signs;
Gamma knife therapy;
Magnetic resonance tomography
- From:
Mongolian Journal of Health Sciences
2026;91(1):245-251
- CountryMongolia
- Language:Mongolian
-
Abstract:
Background:Cerebral cavernous malformations (CCM) present with varied symptoms and are diagnosed only on MRI, which shows characteristic appearances. Genetic factors play a role, with familial cases following an autosomal dominant inheritance pattern.
Case:This is the clinical case of a 48-year-old woman with a history of long-standing arterial hypertension. She was admitted to the Stroke Department with headache, nausea, vomiting, right-sided sensory disturbance, and dysarthria. Based on the clinical presentation and MRI, multiple supra- and infratentorial and intraxial lesions with heterogeneous components were identified, exhibiting hypointense rings on T1- and T2-weighted sequences and a “blooming” effect on T2*/GRE sequences, characteristic of cerebral cavernomas, displaying a “popcorn” appearance.
Conclusion:In CCM, management requires a multidisciplinary approach, with surgical resection the gold standard for symptomatic cases. Accurate determination of familial or sporadic origin is crucial for tailored treatment.
- Full text:202609261428155718742_Тархины_эдийн_цус_харвалтаар_илэрсэн_гэр_бүлийн_тархины_каве.pdf
