Influencing factors and construction of prediction model for physical frailty in elderly patients with multiple digestive tract diseases
10.3969/j.issn.1006-2483.2026.05.034
- VernacularTitle:老年多种消化道疾病患者躯体衰弱影响因素及预测模型构建
- Author:
Tian ZHANG
1
;
Yuanyuan BU
1
Author Information
1. Department of Gastroenterology II, The Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University, Huai'an , Jiangsu 223300, China
- Publication Type:Journal Article
- Keywords:
Digestive tract diseases;
Physical frailty;
Physical function;
Nutritional status
- From:
Journal of Public Health and Preventive Medicine
2026;37(5):160-164
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the risk factors of physical frailty in elderly patients with multiple digestive tract diseases, and to provide reference for clinical intervention. Methods The clinical data of 310 elderly patients with digestive tract diseases admitted to the Affiliated Huai'an No.1 People's Hospital of Nanjing Medical University between May 2020 and May 2025 were retrospectively analyzed. The patients with physical frailty were included in the frailty group, and the remaining patients were assigned into the non-frailty group. The clinical data of the two groups were observed and compared. The influencing factors were explored by multivariate logistic regression analysis, and the prediction model was constructed. Results Among the 310 patients, 77 cases (24.84%) had physical frailty, and 233 cases (75.16%) did not experience frailty. The proportion of patients aged≥75 years, Charlson Comorbidity Index (CCI), Strength, Assistance in walking, Rise from a chair, Climb stairs, Falls (SARC-F) score, 4m walking time and the proportion of patients who failed to complete full-foot-length standing in the frailty group were higher than those in the non-frailty group, while the Mini Nutritional Assessment-Short Form (MNA-SF) score, grip strength, Tinetti balance and gait scale score were lower compared to the non-frailty group (P<0.05). Multivariate logistic regression analysis suggested that SARC-F score was an independent risk factor of physical frailty in elderly patients with digestive tract diseases, and Tinetti score was an independent protective factor (P<0.05). The prediction model was constructed based on multivariate results, and Hosmer-Lemeshow goodness-of-fit test revealed that the model had a good fitting degree (P>0.05). ROC curve analysis indicated that the area under the curve of the model was 0.96 (95%CI: 0.93-1.00). Conclusion The incidence rate of physical frailty is relatively high in elderly patients with digestive tract diseases, and SARC-F score and Tinetti score are associated with its occurrence.
