Risk factors for low blood pressure in patients with refractory heart failure: a discussion based on comorbidities and clinical indicators
10.3969/j.issn.1006-2483.2026.05.022
- VernacularTitle:基于合并疾病与临床指标的顽固性心力衰竭患者低血压发生风险因素分析膳食脂类与载脂蛋白在幽门螺杆菌相关胃黏膜病变中的作用
- Author:
Jiamin ZAN
1
;
Bailing ZHANG
1
;
Fenglai ZHOU
1
;
Shuling ZHANG
1
;
Rong ZHANG
1
;
Tiantian YUAN
1
;
Jingli DAI
1
;
Yuanxin KANG
1
;
Qingqing YANG
1
Author Information
1. Cardiology Department, Affiliated Nantong Hospital of Shanghai University(The Sixth People's Hospital of Nantong), Nantong , Jiangsu 226000, China
- Publication Type:Journal Article
- Keywords:
Refractory heart failure;
Low blood pressure;
Comorbidities
- From:
Journal of Public Health and Preventive Medicine
2026;37(5):101-105
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the occurrence status of low blood pressure (BP) in patients with refractory heart failure (RHF) and its relationship with comorbidities. Methods A retrospective analysis was conducted on the clinical data of 360 patients with RHF who were hospitalized in department of cardiology of Affiliated Nantong Hospital of Shanghai University from May 2021 to May 2025. These patients were divided into the RHF with BP group and the RHF group based on their blood pressure at admission. The general data and comorbidities were compared between both groups. Multivariate logistic regression analysis was used to identify the risk factors for coexisting BP. Results The heart rate (HR), N-terminal pro-B-type natriuretic peptide (NT-proBNP), blood urea nitrogen, high-sensitivity cardiac troponin T, right atrial diameter, proportion of cardiac function grade IV, use rate of diuretics and prevalence rate of dilated cardiomyopathy (DCM) in the RHF with BP group were higher while the high-density lipoprotein cholesterol (HDL-C), albumin, left ventricular ejection fraction, use rate of lipid-lowering drugs and prevalence rate of coronary heart disease were lower compared to the RHF group, and the differences were statistically significant (P<0.05). Multivariate logistic regression analysis suggested that increased HR (OR=1.685, 95%CI: 1.106-2.569), increased NT-proBNP (OR=1.772, 95%CI: 1.138-2.759), decreased HDL-C (OR=0.605, 95%CI: 0.400-0.917) and DCM (OR=1.956, 95%CI: 1.176-3.255) were independent risk factors affecting BP in RHF patients (P<0.05). Conclusion The incidence rate of low blood pressure in elderly RHF patients is about 19.17%. Increased heart rate, increased NT-proBNP, decreased HDL-C and dilated cardiomyopathy are closely linked to the occurrence of low blood pressure, and they can be used as clinically related factors to identify patients at high risk of low blood pressure.
