Factors influencing advanced bone age in early adolescence: a birth cohort study tracking BMI and body composition
10.3969/j.issn.1006-2483.2026.05.014
- VernacularTitle:青春早期儿童骨龄提前的影响因素分析：基于出生队列的BMI、人体成分追踪研究
- Author:
Hui CAO
1
;
Shuangqin YAN
1
;
Guopeng GAO
1
;
Liangliang XIE
1
;
Juan TONG
2
;
Kun HUANG
2
;
Xiaoyan WU
2
;
Fangbiao TAO
2
Author Information
1. Pediatrics department, Maanshan Maternal and Child Health Hospital, Maanshan, Anhui 243000, China
2. Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical Univeristy; Key Laboratory of Population Health Across Life Cycle, Ministry of Education; Anhui Provincial Key Laboratory of Population Health and Aristogenics, Hefei , Anhui 230032, China
- Publication Type:Journal Article
- Keywords:
Bone age;
Body mass index;
Body composition;
Children and adolescents
- From:
Journal of Public Health and Preventive Medicine
2026;37(5):64-67
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the influencing factors of advanced bone age in early adolescence, and to provide a scientific basis for the early identification of children and adolescents with abnormal bone age development. Methods A prospective cohort study design was adopted. From July 2022 to September 2023, height, weight, and body composition data of children were collected, with the baseline age of the study participants being 8.42±0.50 years. Subsequently, from March 2024 to November 2025, these children in the cohort were followed up and their bone age development was monitored. In the end, a total of 1142 participants with complete data were included in the study. Results In early adolescence, there were 239 individuals (20.93%) with early bone age development and 103 (9.02%) with delayed development. The proportion of early bone age development was higher among individuals whose mothers had gestational hypertension during pregnancy, and the difference was statistically significant (χ2=8.90, P<0.05). The proportion of early bone age development was higher among boys, and the difference was statistically significant (χ2=41.69, P＜0.001). Disordered multiclass logistic regression analysis showed that after adjusting for demographic factors, overweight (OR=2.65, 95%CI:1.81-3.88), obesity (OR=6.51, 95%CI: 4.45-9.53), and excessive body fat percentage (OR=4.60, 95% CI: 3.01-7.03) were associated with an increased risk of early bone age development in children and adolescents. Conclusion Being overweight/obese and having an excessive body fat percentage can increase the risk of early bone age development in adolescents.
