Characterization of Filipino patients with cognitive impairment no dementia (CIND) - A consensus diagnosis in a tertiary hospital.
- Author:
Joseree Ann S CATINDIG
;
Simeon M MARASIGAN
;
Encarnita RAYA-AMPIL
;
Ma. Lourdes P CORRALES
- Publication Type:Others
- Keywords:
CindCognitive Impairment No Dementia
- MeSH:
Human;
Male;
Female;
Dementia;
Nervous System Diseases;
Central Nervous System Diseases;
Brain Diseases;
Mild Cognitive Impairment;
Mental Disorders;
Delirium, Dementia, Amnestic, Cognitive Disorders;
Cognition Disorders;
Diagnosis;
Neuropsychological Tests;
Behavioral Disciplines And Activities;
Psychological Tests
- From:
Philippine Journal of Neurology
2008;12(2):38-38
- CountryPhilippines
-
Abstract:
BACKGROUND: CIND is a common condition among the elderly population that has acquired clinical significance with the prevalence in elderly people about twice that of all forums of dementia gathered The concept of cognitive impairment with no dementia CIND has emerged as an important clinical entity because of its possible progression to dementia. Compared to patients diagnosed with no cognitive impairment, CIND patients have a 47% chance of developing dementia in 5 years. OBJECTIVES: This study aims to depict the Filipino patient diagnosed with CIND based on a consensus. It is further our goal to ascertain the prevalence of CIND among patients referred to the Memory Clinic for screening and assessment and also aims to determine if there is a relationship between the patient's profile and certain neuropsychological tests. METHODOLOGY: This is a research study which included all the patients (n=86) referred to the Memory Assessment Clinic of a tertiary hospital. Patients diagnosed with CIND were further evaluated and characterized based on the patient's profile such as general data, history of present illness, past medical history, family history, laboratories and ancillary procedures and neuropsychological examination. Relationship of patient's profile with various neuropsychological test was examined through linear and logistic regression and Spearman's correlation test. RESULTS: Out of the 86 patients evaluated by the Memory Clinic of a tertiary hospital, 17 (19.76%) were diagnosed with CIND. The mean age of the patients with CIND is 70.06 years, majority of whom are females (64.7&) and had 10 years of education. All are married with most of them residing in Metro Manila. All presented with progressive cognitive decline. Years of formal education showed that majority of patients had more than or equal to 10 years. Majority had co-morbid medical conditions. and majority are non-smokers and non-alcoholic beverage drinkers. Average MMSE is 25.88 points; the memory domain is greaty affected. Among the various neuropsychological tests, Verbal fluency and Maze tests were frequently impaired. The rest of the neuropsychological test such as Boston naming, Frontal assessment battery, Clock drawing test were frequently unimpaired. The ADAS Cog mean value was 16.37. MMSE and ADAS Cog showed no significant relationship with the patients profile based on linear and logistic regression as well as Spearman correlation.CONCLUSION: The prevalence of CIND in the memory Clinic of a tertiary hospital is 19.76%. The presentation of these patients is progressive cognitive decline so that careful clinical monitoring is essential. Majority of CIND patients have co-morbid medical conditions (76%). The identification of people at potential risk of dementia with a view to early therapeutic intervention is important, because it may lessen distress for both patient and family, minimize the risk of accidents, prolong autonomy, and perhaps even ultimately prevent the onset of the dementing process itself.
