Active Compounds and Modern Pharmacological Effect of Armeniacae Semen Amarum： A Review
10.13422/j.cnki.syfjx.20260537
- VernacularTitle:苦杏仁活性成分及其现代药理作用研究进展
- Author:
Wen GUO
1
;
Peipei JIN
2
;
Haoran ZHENG
3
;
Lu LIU
3
;
Zeheng CHENG
3
;
Hui QI
4
Author Information
1. Graduate School， Hebei University of Chinese Medicine， Shijiazhuang 050091，China
2. Hebei Yiling Hospital， Shijiazhuang 050091，China
3. Graduate School， Hebei Medical University， Shijiazhuang 050017，China
4. State Key Laboratory for Innovation and Transformation of Luobing Theory， Shijiazhuang 050035，China
- Publication Type:Journal Article
- Keywords:
Armeniacae Semen Amarum;
amygdalin;
antitussive and bronchodilatory effects;
anti-inflammatory effects;
oxidative stress;
antitumor effect
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(19):326-334
- CountryChina
- Language:Chinese
-
Abstract:
Armeniacae Semen Amarum， the dried mature seeds of plants such as Prunus armeniaca var. ansu （Rosaceae）， have a long history for medicinal use. Modern research indicates that the core active compounds of Armeniacae Semen Amarum， such as amygdalin， fatty acids， and volatile oils， exhibit multiple pharmacological effects including antitussive， bronchodilatory， anti-inflammatory， antioxidant， antitumor， antifibrotic， and immunomodulatory effects. Consequently， their potential applications in treating respiratory diseases， tumors， tissue injury， and metabolic disorders have garnered significant attention. However， a systematic integrated analysis of the relationship between the traditional efficacy， modern pharmacology， key material basis， and multi-pathway mechanisms of Armeniacae Semen Amarum remains lacking. Using bibliometric methods combined with CiteSpace visualization technology， this study systematically summarizes the research hotspots on Armeniacae Semen Amarum and its representative component amygdalin， including the key roles in inflammation regulation， apoptosis induction， cell cycle arrest， oxidative stress balance， and fibrosis modulation. This article reviews the research progress in Armeniacae Semen Amarum across from four major dimensions—traditional applications， visualization analysis， material basis， and modern pharmacological studies， providing a reference for the further basic and clinical studies of Armeniacae Semen Amarum in respiratory diseases， oncology， and immune-related disorders.
