INTRODUCTION: We present a case of Polyarteritis Nodosa along the neurocutaneous distribution of the peroneal nerve with characteristic clinical, electrophysiological and histopathological features. Prevalence was estimated to be in the range of 2.0-9.0/ million in the United States. In the Philippines, no reliable data on prevalence is available.

CLINICAL PRESENTATION: We report a case of a 34-year old male, seafarer, working aboard a bulk carrier ship, who presented right lower extremity pain associated with ascending numbness and erythematous patches on the affected area. Review of the family history of similar condition or detectable neuropathies were not found.

DIAGNOSTIC WORK-UP: Initial laboratory tests showed elevated ESR, a non-reactive Hepatitis Profile and negative LE panel. EMG was done and revealed mononeuritis involving the motor and sensory components of the right peroneal nerve. A right peroneal nerve and skin biopsy were done and histopathology showed panmural necrotizing vasculitis along documented blood vessels.

TREATMENT AND FOLLOW-UP: Treatment with corticosteroids was started. Over the months of treatment, patient was noted to have episodes of increased blood pressure. Anti-hypertensive medication was started with Nifedipine 30mg/tab once a day. Renal studies done were normal. Patient's condition improved with resolution of erythematous patches over the affected area, but symptoms of mononeuropathies persisted to some degree.