Trend analysis of changes in blood donor populations in CSBT sentinel sites from 2021 to 2025

Xiaojie GUO; Junhong YANG; Wenqin ZHU; Ruru HE; Guoqiang FENG; Ruiqing JU; Fei TANG; Zhujiang YE; Mingliang YUAN; Xin CHEN; Zhenping LU; Dongfu XIE; Qing XU; Xia HUANG; Jia ZENG

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Trend analysis of changes in blood donor populations in CSBT sentinel sites from 2021 to 2025

VernacularTitle:2021—2025年中国输血协会哨点单位献血者人群变化趋势分析
Author: Xiaojie GUO ¹ ; Junhong YANG ² ; Wenqin ZHU ³ ; Ruru HE ⁴ ; Guoqiang FENG ⁵ ; Ruiqing JU ⁶ ; Fei TANG ⁷ ; Zhujiang YE ⁸ ; Mingliang YUAN ⁹ ; Xin CHEN ¹⁰ ; Zhenping LU ¹¹ ; Dongfu XIE ¹² ; Qing XU ¹³ ; Xia HUANG ² ; Jia ZENG ¹⁴
Author Information

1. Anhui Blood Center, Hefei 230031, China; Working Party on Haemovigilance, Chinese Society of Blood Transfusion, Fuzhou 350004, China
2. Chongqing Blood Center, Chongqing 400052, China; Working Party on Haemovigilance, Chinese Society of Blood Transfusion, Fuzhou 350004, China
3. Fujian Blood Center, Fuzhou 350004, China
4. Nanning Central Blood Station, Nanning 530003, China
5. Shanxi Blood Center, Taiyuan 030024, China
6. Jilin Blood Center, Changchun 130022, China; Working Party on Haemovigilance, Chinese Society of Blood Transfusion, Fuzhou 350004, China
7. Guizhou Blood Center, Guiyang 550002, China
8. Dongguan Central Blood Station, Dongguan 523001, China; Working Party on Haemovigilance, Chinese Society of Blood Transfusion, Fuzhou 350004, China
9. Henan Red Cross Blood Center, Zhengzhou 450014, China
10. Jiangsu Blood Center, Nanjing 210042, China
11. Ganzhou Central Blood Station, Ganzhou 341000, China; Working Party on Haemovigilance, Chinese Society of Blood Transfusion, Fuzhou 350004, China
12. Shanghai Blood Center, Shanghai 200051, China; Working Party on Haemovigilance, Chinese Society of Blood Transfusion, Fuzhou 350004, China
13. Anhui Blood Center, Hefei 230031, China
14. Fujian Geriatric Hospital, Fuzhou 350003, China; Working Party on Haemovigilance, Chinese Society of Blood Transfusion, Fuzhou 350004, China
Publication Type:Journal Article
Keywords: whole blood; apheresis platelet donation; blood donor population; blood donor recruitment; trend analysis
From: Chinese Journal of Blood Transfusion 2026;39(8):1052-1060
CountryChina
Language:Chinese
Abstract: Objective: To analyze the structural changes in whole blood and apheresis platelet donations in Chinese Society of Blood Transfusion (CSBT) sentinel units from 2021 to 2025, and to provide evidence for donor recruitment and blood service management. Methods: Aggregated data reported by sentinel sites were collected and stratified according to six indicators: age, sex, donation history, donation volume, donation site, and organization mode. Pearson χ test, Cramer′V coefficient, Cochran-Armitage trend test and simple linear regression were adopted for analysis. Results: A total of 16 256 973 whole blood donations and 1 576 546 apheresis platelet donations were included. Among whole-blood donations, the proportion of donors aged 18-22 years decreased from 27.30% to 10.60%. The proportion of male donors increased from 58.81% to 63.13%; the proportion of people aged 30 and above increased from 58.40% to 75.30%; the proportion of fixed locations rose from 28.37% to 36.57%; the proportion of social groups increased from 21.69% to 39.69%. The 400-mL donations decreased from 62.12% to 53.46%, while individually initiated voluntary donations remained above 50%. Apheresis platelet donations were predominantly from males, individuals aged 30-39 years, and repeat donors; 2-treatment-unit apheresis platelet donations increased from 67.19% to 74.93%, and individually initiated donations accounted for 92.97%-96.02%. Statistically significant overall annual compositional differences were observed for all six indicators (all P<0.001), whereas linear trends for some sub-categories were not statistically significant. Conclusion: In the participating CSBT sentinel units, among whole blood donations, the proportions of donors aged 18-22 years, university-organized group donations, and donations at blood mobiles decreased, whereas the proportions of organizational group donations and donations at fixed venues increased. The apheresis platelet donation cohort is relatively mature and is evolving toward a high-efficiency donation model. Individual voluntary donation remains the primary organization mode for both donation types. Strategies such as youth donor recruitment, optimized layout of fixed donation sites, and retention of repeat donors should be strengthened to improve the resilience of blood supply.