Current research on dietary therapy for inflammatory bowel disease and central nervous system disorders
10.12025/j.issn.1008-6358.2026.20251543
- VernacularTitle:饮食疗法干预炎症性肠病及中枢神经系统疾病的研究进展
- Author:
Jiexi HUANG
1
;
Weiwei LU
1
Author Information
1. Department of General Practice, Xinhua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China.
- Publication Type:Review
- Keywords:
inflammatory bowel disease;
dietary therapy;
central nervous system disorder;
fatty acid;
gut-brain axis
- From:
Chinese Journal of Clinical Medicine
2026;33(4):721-728
- CountryChina
- Language:Chinese
-
Abstract:
Dietary therapy represents a promising approach to modulate gut microbiota in patients with inflammatory bowel disease (IBD) and may ameliorate certain neurological conditions through the gut-brain axis. The dietary therapy rich in fatty acids has been demonstrated therapeutic efficacy in both IBD and central nervous system (CNS) disorders, mainly manifested as controlling intestinal and neural inflammation through fatty acids. However, robust clinical evidence regarding the efficacy of dietary therapy against neurological manifestations in IBD remains limited. Therefore, this review summarizes the effects of fatty acid-rich dietary therapy in patients with IBD or CNS disorders, as well as the underlying mechanisms of fatty acids, with the aim of providing a reference for the application of such dietary therapy in IBD patients presenting with concurrent CNS manifestations and the development of treatment protocols.
