The pathological diagnostic efficacy of endoscopic ultrasound-guided fine-needle biopsy using a fork-tip needle
10.12025/j.issn.1008-6358.2026.20250400
- VernacularTitle:叉尖型穿刺针在超声内镜引导下细针活检中的病理诊断效能
- Author:
Bahetinuer JIASHAER
1
;
Mei YING
2
;
Baohui SONG
1
;
Tianyin CHEN
1
;
Yiqun ZHANG
1
;
Yunshi ZHONG
1
;
Pinghong ZHOU
1
;
Mingyan CAI
1
Author Information
1. Endoscopy Center, Zhongshan Hospital, Fudan University, Shanghai Collaborative Innovation Center of Endoscopy, Shanghai 200032, China.
2. Department of Gastroenterology, the Second Affiliated Hospital of Shandong First Medical University, Taian 271000, Shandong, China.
- Publication Type:Techniqueandmethod
- Keywords:
endoscopic ultrasound-guided fine-needle biopsy;
endoscopic ultrasound-guided fine-needle aspiration;
fork-tip biopsy needle;
pathological diagnosis rate;
propensity score matching
- From:
Chinese Journal of Clinical Medicine
2026;33(4):689-693
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the pathological diagnosis rate, number of punctures, and applicability to different lesion locations between a fork-tip biopsy needle and a conventional needle. Methods A retrospective collection of data was conducted on 137 patients who underwent endoscopic ultrasound (EUS)-guided fine needle biopsy (novel needle group, n=12) or aspiration (conventional needle group, n=125) at Zhongshan Hospital, Fudan University from January to August 2023. After propensity score matching at a ratio of 1∶5, there were 12 patients in the novel needle group and 60 patients in the conventional needle group. The pathological diagnosis rate and number of punctures were compared between the two groups. The stratified analyses on the size and location of lesions were performed. Results After matching, the pathological diagnosis rate was 91.7% (11/12) in the novel needle group, with a median of 2 punctures; the rate was 61.7% (37/60) in the conventional needle group, with a median of 3 punctures. No statistically significant differences in pathological diagnosis rate and number of punctures were observed between the two groups. Subgroup analysis showed that for lesions ≥20 mm, there was no significant difference in the number of punctures between the novel and conventional needles. The novel needle achieved a significantly higher pathological diagnosis rate for subepithelial tumors compared with the conventional needle (100.0% vs 30.4%, P＝0.019), whereas no significant differences were found for pancreatic masses or lymph node lesions. Conclusions Compared with EUS-guided aspiration using the conventional needle, EUS-guided biopsy using the novel fork-tip needle shows a trend toward a higher pathological diagnosis rate, with particular advantages in subepithelial tumors.
