Treatment of Chemotherapy-Induced Myelosuppression After Gastric Cancer Surgery：Based on the Relationship Among Spleen，Ying （荣） Qi，and Bone Marrow
10.13288/j.11-2166/r.2026.17.017
- VernacularTitle:从脾、荣气、骨髓的关系论治胃癌术后化疗致骨髓抑制
- Author:
Zerun CHENG
1
;
Yuting SUN
2
;
Wenkang ZHANG
1
;
Guanghui ZHU
2
;
Jie LI
2
Author Information
1. Beijing University of Chinese Medicine，Beijing，100029
2. Guang'anmen Hospital，China Academy of Chinese Medical Science
- Publication Type:Journal Article
- Keywords:
gastric cancer;
myelosuppression;
chemotherapy;
spleen;
ying （荣） qi;
bone marrow
- From:
Journal of Traditional Chinese Medicine
2026;67(17):1910-1914
- CountryChina
- Language:Chinese
-
Abstract:
Patients with gastric cancer undergoing postoperative chemotherapy often develop myelosuppression due to direct injury to the spleen and stomach caused by surgery， depletion of healthy qi by chemotherapy， impaired generation of ying （荣） qi due to spleen and stomach deficiency， and the accumulation of drug toxicity， which prevents ying qi from reaching and nourishing the bone marrow. Consequently， the bone marrow loses its nourishment and becomes unable to generate blood， leading to myelosuppression. This paper proposes that the core pathogenesis involves failure of the middle jiao （焦） pivot function， dysfunction of ying qi circulation， and insufficient nourishment of essence and marrow. Accordingly， Shengxian Decoction （升陷汤） combined with Danggui Buxue Decoction （当归补血汤） is used as the principal prescription to tonify the middle jiao and uplift center qi， thereby remedying the fundamental insufficiency of ying qi. Modified Compound Danshen Decoction （复方丹参饮） is applied to promote qi circulation， resolve stasis， remove toxin， and unblock collaterals， thereby resolving the obstruction preventing ying qi from reaching the bone marrow. Modified Dabuyuan Decoction （大补元煎） combined with Erzhi Pill （二至丸） is taken as the foundational formula to cultivate the root， replenish marrow， thereby modulating hematopoiesis in bone marrow.
