Strategies for the application of ultrasound in early and differential diagnosis of hepatocellular carcinoma
- VernacularTitle:超声在肝细胞癌早期诊断与鉴别诊断中的应用策略
- Author:
Jiawei HU
1
;
Yukun LUO
1
Author Information
- Publication Type:Journal Article
- Keywords: Carcinoma， Hepatocellular; Ultrasonography; Diagnosis
- From: Journal of Clinical Hepatology 2026;42(7):1501-1506
- CountryChina
- Language:Chinese
- Abstract: Hepatocellular carcinoma （HCC） often has an insidious onset， and early diagnosis and accurate differential diagnosis are critical for improving the prognosis of patients. Ultrasound remains an important radiological examination for the screening and initial assessment of high-risk populations due to its advantages of convenience， real-time monitoring， repeatability， and suitability for dynamic follow-up. With the development of ultrasound technologies in recent years， the application of ultrasound in HCC has gradually expanded from lesion detection to lesion characterization， differential diagnosis， and prognostic evaluation. With reference to the clinical needs for the early and differential diagnosis of HCC， this article reviews the application value， clinical localization， and limitations of gray-scale ultrasound， Doppler ultrasound， and contrast-enhanced ultrasound in HCC， with a focus on their application in the evaluation and differential diagnosis of small HCC. It highlights that comprehensive evaluation should be performed based on liver background， lesion morphology， blood flow features， enhancement patterns， and dynamic changes during follow-up， so as to improve the early and differential diagnosis of HCC.
