Emergency testing and analysis of a mixed poisoning incident involving methyl acetate and dimethyl carbonate
10.20001/j.issn.2095-2619.20260220
- VernacularTitle:乙酸甲酯和碳酸二甲酯混合中毒事件应急检测分析
- Author:
Guanlin CHEN
1
;
Yao GUO
;
Jianyi LIANG
;
Qiang TAN
;
Jiaheng HE
;
Wanxia CHEN
;
Yingqing XIE
;
Weifeng RONG
;
Banghua WU
Author Information
1. Foshan Institute of Occupational Disease Prevention and Control (Foshan Occupational Health Research Institute), Foshan, Guangdong 528000, China
- Publication Type:Journal Article
- Keywords:
Methyl acetate;
Dimethyl carbonate;
Occupational poisoning;
Chemical poisoning;
Investigation
- From:
China Occupational Medicine
2026;53(1):116-120
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the emergency testing results of a mixed poisoning incident involving methyl acetate and dimethyl carbonate in a composite fabric processing enterprise. Methods A mixed poisoning incident involving methyl acetate and dimethyl carbonate occurred at a composite fabric processing enterprise in a city of Guangdong Province. On-site occupational health investigation data and laboratory testing results related to this incident were collected, and an integrated analysis was conducted. Results The on-site occupational health investigation revealed inadequate ventilation and non-standard use of personal protective equipment. Volatile organic component analysis of raw and auxiliary materials showed that methyl acetate and dimethyl carbonate had relatively high percentages of peak area among all used volatile organic chemical agents in post-incident emergency testing, accounting for 65.10% and 38.25%, respectively. The exposure concentration of short term (CSTE) of methyl acetate in the production line air was 15.13 mg/m³. In the chemical storage area, CSTE of methyl acetate and methanol were 451.04 and <0.21 mg/m³, respectively, all below their respective occupational exposure limits (500.00 and 50.00 mg/m³). In the poisoned workers, blood methanol, blood formic acid, and urinary formic acid levels were 147, 414, and 4 389 mg/L, respectively. Conclusion Occupational exposure to methyl acetate and dimethyl carbonate may lead to acute occupational poisoning and cause health damage. Employers should fulfill their responsibilities for occupational disease prevention by ensuring proper operation of protective facilities, while workers should enhance awareness of occupational disease prevention and correctly use personal protective equipment.
