Establishment of Objective Indicators and Evaluation System for "Excellent Shape and High Quality" Characteristics of Authentic Ophiopogonis Radix
10.13422/j.cnki.syfjx.20260215
- VernacularTitle:麦冬道地药材的“优形优质”特征客观指标及评价体系建立
- Author:
Bocheng WANG
1
;
Yan JIN
2
;
Yuanbai LI
3
;
Danping FAN
1
;
Guanglei MA
4
;
Lei LEI
3
;
Wei LIU
2
;
Yuan YUAN
1
Author Information
1. Experimental Research Center， China Academy of Chinese Medical Sciences， Beijing 100700， China
2. National Resource Center for Chinese Materia Medica， China Academy of Chinese Medical Sciences，Beijing 100700，China
3. Institute of Information on Traditional Chinese Medicine， China Academy of Chinese Medical Sciences， Beijing 100700，China
4. School of Pharmacy， Zhejiang University，Hangzhou 310058，China
- Publication Type:Journal Article
- Keywords:
Ophiopogonis Radix;
authenticity;
excellent shape and high quality;
objective indicators;
quality evaluation
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(18):7-15
- CountryChina
- Language:Chinese
-
Abstract:
ObjectiveTo construct a new quality classification method for Ophiopogonis Radix by systematically quantifying and integrating its appearance traits and bioactive components as objective indicators according to the theory of excellent shape， high quality， and superior effect of authentic medicinal materials. MethodsWith Ophiopogonis Radix from Zhejiang （a traditionally recognized authentic variety） as the research model， extensive samples were collected. Through textual research on classical herbal literature and modern references， root tuber length and hardness were selected as representative indicators of traditional appearance traits. These indicators were accurately measured by a digital vernier caliper and a universal testing machine for objective quantification. According to prescription data and literature review results， total saponins， total polysaccharides， and total flavonoids were chosen as key component indicators， and their content was determined. Descriptive statistics， cluster analysis， and other methods were comprehensively employed to identify the core objective indicators and their threshold ranges defining the excellent shape and high quality. The constructed evaluation system was subsequently applied to Ophiopogonis Radix from Zhejiang and Sichuan to verify its applicability. ResultsThe core quantitative indicators for the excellent shape and high quality of Ophiopogonis Radix were determined as follows： Length≥2.09 cm， hardness≤7.0 N， and content of total saponins， total polysaccharides， and total flavonoids not lower than 0.12%， 1.69%， and 0.13%， respectively. Verification results showed that this evaluation system could effectively identify Ophiopogonis Radix samples from Zhejiang， with the results consistent with traditional high-quality recognition. Its successful application to the samples from Sichuan further confirmed its cross-region universality. ConclusionThis study established an objective indicator-based evaluation system for the excellent shape and high quality of Ophiopogonis Radix， which breaks through the reliance on production regions. This system provides theoretical and methodological bases for precise quality control， scientific grading， and quality-based pricing of Ophiopogonis Radix， offering an innovative paradigm for the objective evaluation of authentic medicinal materials.
