Staged Treatment Strategy for Bleeding Events in Panvascular Disease Guided by the Theory of "Guarding the Channel Passages"
10.13288/j.11-2166/r.2026.16.016
- VernacularTitle:“守经隧”理论指导下泛血管疾病出血事件的分期论治思路
- Author:
Chen CHEN
1
;
Pengfei CHEN
1
;
Zhiyan MA
1
;
Wenxi YU
1
;
Lingli ZHAO
1
;
Hua QU
1
;
Changgeng FU
1
;
Dazhuo SHI
1
Author Information
1. Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing,100091
- Publication Type:Journal Article
- Keywords:
panvascular disease;
bleeding events;
guarding the channel passages
- From:
Journal of Traditional Chinese Medicine
2026;67(16):1789-1792
- CountryChina
- Language:Chinese
-
Abstract:
Patients with panvascular disease (PVD) often experience bleeding events while receiving standard antithrombotic therapy. Based on the theory of "guarding the channel passages", the retention of blood stasis is considered as a crucial pathological basis for PVD. The combination of the retention of blood stasis and the failure of the channel passages to contain blood constitutes the core pathogenesis of bleeding events in this condition. According to their pathogenesis and clinical characteristics, bleeding events in PVD are categorized into a bleeding stage and a stable stage. During the bleeding stage, treatment should focus on stanching bleeding and dispersing stasis to restore normal circulation in the channel passages. During the stable stage, treatment should aim to dispel stasis and generate new blood to harmonize the channel passages. In clinical practice, physicians should dynamically weigh the risks of bleeding and ischemia against the intensity of antithrombotic therapy. The ultimate goal is to harmonize qi and blood and ensure that blood remains properly contained within the channel passages, thereby reducing the risk of bleeding events and enhancing overall patient benefit.