Cutaneous metastases from nasopharyngeal carcinoma: A rare manifestation

Halimuddin SAWALI; Mohd Razif Mohamad YUNUS; Ong Cheng AI; Primuharsa Putra SABIR HUSIN ATHAR

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Cutaneous metastases from nasopharyngeal carcinoma: A rare manifestation

Author: Halimuddin SAWALI ¹ ; Mohd Razif Mohamad YUNUS ² ; Ong Cheng AI ¹ ; Primuharsa Putra SABIR HUSIN ATHAR ³
Author Information

1. Department of Otorhinolaryngology Head and Neck Surgery , Hospital Queen Elizabeth, Sabah, Malaysia, Malaysia
2. Department of Otolaryngology Head and Neck Surgery, Universiti Kebangsaan Malaysia Medical Centre, Philippines
3. Ear, Nose, Throat-Head and Neck Consultant Clinic, KPJ Seremban Specialist Hospital, Philippines
Publication Type:Case report
Keywords: 53 Years Old43 Years OldCutaneous MetastasesSkin MetastasesChemo-radiotherapyTreatment
MeSH: Human; Male; Female; Middle Aged; Adult; Nasopharynx; Nasopharyngeal Neoplasms-radiotherapy, Drug Therapy, Biopsy; Nasopharyngeal Carcinoma; Neoplasm Metastasis; Neoplasms; Early Detection Of Cancer; Diagnosis; Therapy; Therapeutics
From: Philippine Journal of Otolaryngology Head and Neck Surgery 2010;25(2):32-35
CountryPhilippines
Abstract:
OBJECTIVES: In this article, we report on two unusual cases of advanced nasopharyngeal cacinoma (NPC) with distant cutaneous metastases.

METHODS:
Design: Case Report
Setting: Tertiary Referral Center
Patients: Two

RESULTS: Two patients with advanced NPC developed multiple nodular skin metastases, one after completing radiotherapy and another during concurrent chemo-radiotherapy. Biopsies of these skin lesions confirmed metastatic NPC and both patients succumbed to the disease.

CONCLUSION: Nasopharyngeal carcinoma with skin metastases carries a very poor prognosis. Early detection, diagnosis and treatment are still the best management strategy for nasopharyngeal carcinoma.