Gigantism is an extremely rare condition with only approximately 100 cases reported to date and no known reported case in the Philippines thus far. In this paper, we describe a case of pituitary gigantism who presented with primary amenorrhea, absent breast development and tall stature in a 19 year old, nulligravid, college varsity student prompting referral to a reproductive endocrinologist. How this condition affects our patient's sexual development and her future reproductive capability, the associated medical complications of the disease and the benefits and risks associated with the different treatment modalities administered will be discussed.