Rapid fetal fibronectin alone and in combination with cervical length in predicting preterm delivery among symptomatic pregnant women in a Philippine tertiary hospital: A retrospective cohort study from 2009 to 2012.
- Author:
Joanna Pauline Chua URSUA
;
Ma. Rosario Castillo CHENG
- Publication Type:Journal Article, Original
- MeSH: Human; Female; Pregnancy; Cervical Length Measurement; Fn1 Protein, Human; Fibronectins; Obstetric Labor, Premature; Premature Birth; Parturition; Delivery, Obstetric
- From: Philippine Journal of Obstetrics and Gynecology 2013;37(2):89-96
- CountryPhilippines
-
Abstract:
BACKGROUND: The objective of the study was to determine the likelihood of delivery given a positive or negative rapid fetal fibronectin test result in symptomatic pregnant women in a Philippine tertiary hospital. Another objective was to determine if the likelihood of delivery is increased when fetal fibronectin is combined with cervical length assessment.
METHODS: Medical records from 2009 to 2012 of patients between 24 weeks and 34 weeks and 6 days gestation with symptoms of preterm labor were retrieved and selected for this study. Rapid beside fetal fibronectin results and cervical length measurements obtained via ultrasonography were gathered along with the interval duration from fibronectin testing, cervical length measurement and delivery.
RESULTS: Thirty-one patients had fetal fibronectin samples and outcome data. The admission-to-delivery interval was 33.6 days shorter in the group with positive fetal fibronectin results than in the group with negative fetal fibronectin results. (20.2 + 15.48 compared with 53.8 + 26.95; P