- VernacularTitle:智能体技术在病理诊断流程中的应用进展
- Author:
Lianzhi LING
1
;
Huanwen WU
1
;
Zhiyong LIANG
1
Author Information
- Publication Type:Journal Article
- Keywords: computational pathology; artificial intelligence-assisted diagnosis; agent
- From: Medical Journal of Peking Union Medical College Hospital 2026;17(4):1003-1011
- CountryChina
- Language:Chinese
-
Abstract:
With the rapid advancement of artificial intelligence technology, computational pathology has evolved from task-specific models to foundation models capable of supporting multiple organs, diseases, and downstream tasks. However, existing methods remain limited to single-pass inference on images and are unable to fully emulate the complex diagnostic processes encountered in real-world clinical settings. In recent years, large language models have driven the development of agent-based paradigms. By leveraging capabilities such as navigation, reasoning, and tool use, these frameworks offer a novel approach for modeling complex diagnostic workflows. Framed within the context of clinical pathology diagnostic processes, this article systematically reviews the key challenges and advances in computational pathology research across three stages: preliminary overview, diagnostic analysis, and report writing, and discusses the current functional roles and implementation approaches of agent-based technologies at each stage. Although validation scenarios in existing studies remain limited, the core modules and methods required to construct a pathology diagnostic agent system are largely in place. Agent-related technologies are expected to facilitate the development of a clinically deployable intelligent assistance platform for pathology diagnosis.

