Syndrome Differentiation and Treatment Approaches for Childhood IgA Vasculitis Nephritis from

Xiaoqing ZHENG; Yifan LI; Ying DING; Shanshan XU; Long WANG; Yaping XING; Wenchao XING

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Syndrome Differentiation and Treatment Approaches for Childhood IgA Vasculitis Nephritis from "Heat，Stasis and Deficiency"

VernacularTitle:从热、瘀、虚探讨儿童IgA血管炎性肾炎的辨治
Author: Xiaoqing ZHENG ¹ ; Yifan LI ² ; Ying DING ¹ ; Shanshan XU ¹ ; Long WANG ³ ; Yaping XING ¹ ; Wenchao XING ¹
Author Information

1. Pediatric Hospital of the First Affiliated Hospital of Henan University of Traditional Chinese Medicine，Zhengzhou，450000
2. First Teaching Hospital of Tianjin University of Traditional Chinese Medicine
3. Medical College of Pediatrics，Henan University of Chinese Medicine
Publication Type:Journal Article
Keywords: IgA vasculitis nephritis; heat; stasis; deficiency; Qingre Zhixue Formula （清热止血方）; children
From: Journal of Traditional Chinese Medicine 2026;67(15):1673-1676
CountryChina
Language:Chinese
Abstract: The core pathogenesis of childhood IgA vasculitis nephritis （IgAVN） lies in the intermingled conditions of heat， stasis and deficiency. Deficiency is the fundamental cause， while heat acts as the predominant manifestation at the initial stage， and stasis serves as the key factor leading to protracted illness. Based on this understanding， the overall therapeutic principle of clearing heat and cooling blood， dissolving stasis and unblocking collaterals， reinforcing healthy qi and consolidating the root is established. A self-formulated Qingre Zhixue Formula （清热止血方） is used as the basic prescription. According to the characteristics of different disease stages， childhood IgAVN is further classified into three main syndrome types， including blood heat with stasis obstruction， deficiency of both qi and yin， and deficiency of both spleen and kidney， with corresponding syndrome-based treatments. Throughout the treatment process， emphasis is placed on dissolving stasis and unblocking collaterals， while protecting the spleen and stomach of children and maintaining healthy qi. This paper provides new perspectives for diagnosis and treatment of childhood IgAVN with traditional Chinese medicine.