Exploring the Pathogenesis Evolution and Treatment Strategies of Skin Cancer from the Perspective of "Spleen Deficiency， Sweat Pore Obstruction，and Toxin Accumulation"
10.13288/j.11-2166/r.2026.15.007
- VernacularTitle:从“脾虚-玄闭-毒结”探析皮肤癌的病机演变及辨治策略
- Author:
Yiwei ZHONG
1
;
Xueqian WANG
1
;
Ruijuan CAI
1
;
Ying TAN
1
;
Baojin HAN
1
;
Hongsheng LIN
1
Author Information
1. Guang'anmen Hospital， China Academy of Chinese Medical Sciences，Beijing，100053
- Publication Type:Journal Article
- Keywords:
skin cancer;
spleen;
sweat pore;
skin and body hair
- From:
Journal of Traditional Chinese Medicine
2026;67(15):1618-1622
- CountryChina
- Language:Chinese
-
Abstract:
This paper discusses the pathogenesis and treatment strategies of skin cancer based on the theory of "spleen deficiency-sweat pore obstruction-toxin accumulation". It is believed that although the disease is located in the skin and body hair， it is not only the localized disorder but closely related to the imbalance of qi and blood of zang-fu （脏腑） organs. The core of the disease is the synergistic disorder of spleen， sweat pore， and skin and body hair. The disease progression follows a dynamic evolution from spleen deficiency with loss of nourishment， initial closure of sweat pore to binding of dampness and stasis with obstruction of sweat pore， and then to cancer toxin consolidation with damage to sweat pore. Based on this， three principles of building earth， opening sweat pore and attacking toxin are established. The method of fortifying spleen and raising the clear aims to consolidate the root and restore validity， with commonly used prescriptions including modifications of Buzhong Yiqi Decoction （补中益气汤）， Liujunzi Decoction （六君子汤） and Guipi Decoction （归脾汤）. The method of opening sweat pores with acrid-moistening medicinals is suggested when dredging and unblocking the sweat pore， commonly using acrid and warm dispersing medicinals， supplemented with herbs that nourish fluids and moisten dryness. The method of clearing heat and removing toxin is to break cancer toxin directly， and modifications of prescriptions such as Wuwei Xiaodu Beverage （五味消毒饮）， Xiaolei Pills （消瘰丸） and Xihuang Pills （犀黄丸） are commonly used. These approaches provide valuable ideas for the prevention and treatment of skin cancer with traditional Chinese medicine.
