Chemical Constituents and Pharmacological Effect of Euodiae Fructus： A Review
10.13422/j.cnki.syfjx.20260543
- VernacularTitle:吴茱萸化学成分和药理作用研究进展
- Author:
Xue ZHAN
1
;
Yu MOU
1
;
Xuelian ZHANG
1
;
Jianyuan TANG
1
Author Information
1. Affiliated Hospital of Chengdu University of Traditional Chinese Medicine， Chengdu 610075， China
- Publication Type:Journal Article
- Keywords:
Euodiae Fructus;
chemical constituent;
pharmacological effect;
mechanism of action;
toxicity and safety
- From:
Chinese Journal of Experimental Traditional Medical Formulae
2026;32(17):335-346
- CountryChina
- Language:Chinese
-
Abstract:
Euodiae Fructus， a commonly used Chinese medicinal herb， has been widely used to treat gastrointestinal disorders， headaches， and vomiting， possessing significant medicinal value. According to traditional Chinese medical theory， Euodiae Fructus has the following effects： warming the middle to disperse cold， suppressing adverse Qi to relieve vomiting， and soothing the liver to alleviate pain. It is commonly used to treat diseases associated with cold stagnation in the liver and stomach， as well as gastrointestinal dysfunction. In recent years， as modern research on traditional Chinese medicine has advanced， increasing attention has been paid to the chemical constituents and pharmacological effects of Euodiae Fructus. Studies have isolated and identified various chemical constituents in this herb， including alkaloids， terpenoids， phenols， steroids， and volatile oils. Among them， alkaloids and terpenoids have been most extensively investigated. Studies suggest that Euodiae Fructus and some of its active constituents exhibit anti-inflammatory， anti-tumor， cardiovascular and cerebrovascular protective， and metabolic syndrome-regulating effects. However， current studies mainly focus on a few representative constituents. A systematic understanding of the overall bioactive material basis and mechanisms of action of this herb still requires further investigation. Additionally， more in vivo pharmacodynamic studies， clinical evaluations， and toxicological assessments are needed. This article summarizes recent advances in the pharmacological effects of Euodiae Fructus based on a systematic review of its major chemical constituents， aiming to provide a reference for further research and the rational development and utilization of this medicinal herb.
