Prevalence and characteristics of polycystic ovary syndrome (PCOS) in Filipino women diagnosed with endometrial cancer: A five-year retrospective study.
- Author:
Genevieve M ORTEGA
1
;
Angela S AGUILAR
1
Author Information
- Publication Type:Journal Article, Original
- MeSH: Human; Female; Adult; Endometrial Carcinoma; Polycystic Ovary Syndrome; Prevalence
- From: Philippine Journal of Reproductive Endocrinology and Infertility 2016;13(2):62-71
- CountryPhilippines
-
Abstract:
Methodology: A review of women with histopathologically-confirmed endometrial carcinoma treated at the Philippine General Hospital from June 2010 to June 2015 was performed. Data were extracted regarding age at diagnosis of endometrial cancer, gravidity, parity, menstrual history, presence of polycystic ovaries on ultrasound, body mass index, abnormal blood glucose, histologic type and stage of the disease at the time of diagnosis of endometrial cancer.
Results: Sixty-one out of 487 (12.53%) endometrial cancer patients were identified to have PCOS. Thirty-four percent of those identified were diagnosed with endometrial cancer at ages 30 to 39 (p=0.00). Majority were nulligravid (80.33%) and nulliparous (81.97%). There was direct correlation with obesity with highest prevalence seen in Obese Type II (62.30%, p=0.00). Prevalence of diabetes mellitus in those identified PCOS was statistically significant (78.69%, p=0.00). Prevalence of endometrial Type I cancer and Stage I disease were 78.69% and 62.30%, respectively, but both were not statistically significant.
Conclusion: There is increased prevalence of PCOS in endometrial cancer patients who are at the premenopausal age group (30-39 years old) and they are likely nulligravid, nulliparous, obese, with a history of abnormal blood glucose.
