Relationship between shear wave elastography parameters and APRI and Child-Pugh grading in patients with hepatitis B cirrhosis
10.13491/j.issn.1004-714X.2026.03.019
- VernacularTitle:剪切波弹性成像参数及APRI与乙肝肝硬化患者Child-Pugh分级的关系分析
- Author:
Wen ZHAO
1
;
Mengsi XU
1
;
Chunfeng YU
1
;
Jun CHEN
2
Author Information
1. Department of Ultrasound, Affiliated Hospital of Hubei University for Nationalities , Enshi 445000, China.
2. Department of Endocrinology, Affiliated Hospital of Hubei University for Nationalities , Enshi 445000, China.
- Publication Type:OriginalArticles
- Keywords:
Shear wave elastography;
APRI;
Child-Pugh grading;
Liver stiffness;
Hepatitis B cirrhosiss
- From:
Chinese Journal of Radiological Health
2026;35(3):433-438
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the associations of shear wave elastography (SWE) parameters and AST-to-platelet ratio index (APRI) with Child-Pugh grade in patients with hepatitis B cirrhosis. Methods The clinical data of 103 patients with hepatitis B cirrhosis who underwent SWE and APRI testing between July 2022 and October 2024 were retrospectively analyzed. These patients comprised the observation group. The clinical data of 99 non-cirrhotic patients were retrospectively analyzed and the patients were enrolled as control group. Liver stiffness (LS), spleen stiffness (SS), APRI and Child-Pugh score were compared in the two groups. According to Child-Pugh grading, the 103 cirrhosis patients were divided into three groups: Group A (grade A, 5-6 points, n=35), Group B (grade B, 7-9 points, n=38), and Group C (grade C, 10-15 points, n=30). SWE parameters and APRI were compared among the three groups. Pearson correlation analysis was used to examine the correlations of LS, SS, and APRI with Child-Pugh score. Results SWE parameters, APRI, and Child-Pugh scores were significantly higher in the observation group than in the control group (P<0.05). Among the three cirrhosis groups, SWE parameters and APRI were highest in Group C, followed by Group B, and lowest in Group A (P<0.05). SWE parameters and APRI were significantly positively correlated with Child-Pugh score (P<0.05). Conclusion SWE parameters and APRI are positively correlated with Child-Pugh grade and are useful for assessing the severity of liver cirrhosis.
