Application value of multi-slice spiral computed tomography in diagnosis of early-stage lung cancer
10.13491/j.issn.1004-714X.2026.03.017
- VernacularTitle:多层螺旋CT在早期肺癌诊断中的应用价值
- Author:
Desheng JIANG
1
;
Xiaoyun ZHANG
1
;
Jin WANG
2
Author Information
1. Department of Imaging, West Anhui Health Vocational College Affiliated Hospital, Lu'an 237000, China.
2. Departmen of Pathology, West Anhui Health Vocational College Affiliated Hospital, Lu'an 237000, China.
- Publication Type:OriginalArticles
- Keywords:
Multi-slice spiral computed tomography;
Lung cancer;
Diagnosis
- From:
Chinese Journal of Radiological Health
2026;35(3):421-426
- CountryChina
- Language:Chinese
-
Abstract:
Objective This study aims to evaluate the diagnostic efficacy of multi-slice spiral CT in early lung cancer and provide evidence for clinical differentiation. Methods A retrospective analysis was conducted on the clinical data of 86 patients with early-stage lung cancer admitted to our hospital between March 2020 and February 2025. All patients underwent MSCT examination. Using pathological examination as the gold standard, the consistency between MSCT and the gold standard was analyzed. CT sign differences among patients with different pathological types of lung cancer were compared. Pearson correlation analysis was used to analyze the relationships between CT signs and the degree of adenocarcinoma infiltration. Results MSCT examination showed positive findings in 75 cases of adenocarcinoma, with a sensitivity of 97.40%, a specificity of 88.89%, a positive predictive value of 98.68%, a negative predictive value of 80.00%, an accuracy of 96.51%, and a Kappa value of 0.823. Significant differences were found in the proportions of tumor maximum diameter > 2 cm, vacuole sign, ground-glass opacity sign, lobulation sign, spiculation sign, air bronchogram sign, pleural indentation sign, and vascular convergence sign (P<0.05), and these proportions increased progressively from carcinoma in situ to minimally invasive adenocarcinoma to invasive adenocarcinoma. Pearson correlation analysis showed that tumor maximum diameter, vacuole sign, ground-glass opacity sign, and pleural indentation sign were positively correlated with adenocarcinoma, while spiculation sign and vascular convergence sign were negatively correlated with adenocarcinoma (P<0.05). Conclusion MSCT demonstrates high diagnostic efficiency for early-stage lung adenocarcinoma and can provide a reference for early clinical evaluation.
