Advancements in the application of gas chromatography-ion migration spectrometry（GC-IMS）in traditional Chinese medicine research
10.12206/j.issn.2097-2024.202409007
- VernacularTitle:气相色谱-离子迁移谱技术在中药研究中的应用进展
- Author:
Haiyun WU
1
;
Tian YANG
1
;
Chi ZHANG
2
;
Wenyi LIANG
2
;
Juan SU
2
Author Information
1. Class 2022 of Chinese Medicine.
2. National Demonstration Center for Experimental Military Pharmacy Education, Naval Medical University, Shanghai 200433, China.
- Publication Type:Reviews
- Keywords:
GC-IMS;
traditional Chinese medicine;
volatile components;
processing;
quality analysis
- From:
Journal of Pharmaceutical Practice and Service
2026;44(7):341-345
- CountryChina
- Language:Chinese
-
Abstract:
Traditional Chinese medicine contains a variety of volatile components （VOCs） such as terpenes and aliphatics, which have significant pharmacological activities, and are commonly analyzed by gas chromatography （GC） and gas chromatography-mass spectrometry （GC-MS）. Although the separation ability is strong, the samples need to be pre-treated and the analysis time is long. In recent years, the combination of GC and ion migration spectrometry （IMS） has been widely used in the academic community. The combination of high separation ability of GC and rapid reaction ability of IMS has the advantages of no sample pretreatment, fast analysis time, low detection limit and simple operation. It is increasingly used in traditional Chinese medicine research. The working principle of GC-IMS was introduced, the application in VOCs research of traditional Chinese medicine was summarized, and the future development direction was prospected in this paper.
