Prognosis and its influencing factors in patients with hypertension complicated with heart failure
10.3969/j.issn.1006-2483.2026.04.036
- VernacularTitle:高血压合并心力衰竭患者预后状况及影响因素
- Author:
Jun QIU
1
;
Hongyan CUI
1
;
Lingyan SU
1
Author Information
1. Department of Cardiovascular Internal Medicine，Nantong Third People's Hospital, Nantong , Jiangsu 226000, China
- Publication Type:Journal Article
- Keywords:
Hypertension;
Heart failure;
Prognosis;
Predictive value
- From:
Journal of Public Health and Preventive Medicine
2026;37(4):173-176
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the prognosis and its influencing factors in patients with hypertension complicated with heart failure (HF). Methods A total of 381 patients with hypertension and HF who were treated in our hospital from March 2022 to April 2025 were chosen. The patients were followed up for the prognosis within 6 months and split into good prognosis group (n=266) and poor prognosis group (n=115). The clinical data of the two groups were compared and analyzed. Multivariate Logistic regression analysis was used to determine the influencing factors of poor prognosis. Results The group with poor prognosis had higher proportions of atrial fibrillation and New York Heart Association (NYHA) Class III-IV, as well as increased left ventricular end-diastolic diameter (LVED), left ventricular end-systolic diameter (LVES), interventricular septum thickness (IVS), and left ventricular posterior wall thickness (LVPW) compared to the group with good prognosis (P<0.05). Additionally, levels of systolic blood pressure (SBP), N-terminal pro-B-type natriuretic peptide (NT-proBNP), total cholesterol (TC), low-density lipoprotein (LDL), creatinine (Cr) were elevated (P<0.05), while left ventricular ejection fraction (LVEF) was decreased (P<0.05). NYHA classification, LVEF, LVED, LVPW, NT-proBNP were independent influencing factors of poor prognosis in patients with hypertension complicated with HF (P<0.05). Conclusion NYHA classification, LVEF, LVED, LVPW and NT-proBNP are closely related to the poor prognosis of patients with hypertension and HF.
