Correlation between NRS-2002 score and risk of acute exacerbation within 1 year in patients with stable COPD
10.3969/j.issn.1006-2483.2026.04.013
- VernacularTitle:NRS-2002评分与COPD稳定期患者1年内急性加重风险的相关性
- Author:
Xinlan LI
1
;
Jing YANG
1
;
Jing ZHAO
1
Author Information
1. Department of Respiratory and Critical Care Medicine, Mianyang Hospital Affiliated to School of Medicine of University of Electronic Science and Technology of China·Mianyang Central Hospital, Mianyang , Sichuan 621000, China
- Publication Type:Journal Article
- Keywords:
Chronic obstructive pulmonary disease;
Acute exacerbation;
Nutritional risk screening 2002 score
- From:
Journal of Public Health and Preventive Medicine
2026;37(4):61-65
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the correlation between nutritional risk screening 2002 (NRS-2002) score and risk of acute exacerbation during 1-year follow-up in patients with chronic obstructive pulmonary disease (COPD), and to analyze the predictive value of NRS-2002 score on acute exacerbation. Methods A total of 314 patients hospitalized for acute exacerbation of COPD in the hospital were included between January 2021 and December 2024. All patients reached the stable disease standard after standardized treatment, and completed the NRS-2002 nutritional risk score assessment and other clinical data collection before discharge. 1-year follow-up was performed after discharge. According to whether acute exacerbation occurred again, they were classified into 62 cases in the acute exacerbation group and 252 cases in the non-acute exacerbation group. Univariate and logistic multivariate regression analyses were performed to analyze the risk factors for acute exacerbation. The correlation between NRS-2002 score and acute exacerbation risk during 1-year follow-up was analyzed by Spearman correlation analysis. ROC curve was drawn to analyze the predictive value of NRS-2002 score on acute exacerbation. Results The body mass index (BMI) and forced expiratory volume in one second as a percentage of predicted value (FEV1%) in the acute exacerbation group were lower while the proportion of smoking and NRS-2002 score were higher compared to the non-acute exacerbation group (P<0.05). After logistic multivariate analysis, it was found that low BMI, low FEV1%, smoking history, and NRS-2002 score were high risk factors for acute exacerbation in patients with stable COPD within 1 year (P<0.05). Spearman correlation indicated that NRS-2002 score exhibited a positive association with acute exacerbation risk (r=0.546, P<0.05). ROC curve analysis suggested that the area under the curve (AUC), sensitivity and specificity of NRS-2002 score in predicting acute exacerbation were 0.900, 69.35% and 98.41% respectively. Conclusion NRS-2002 score is positively linked to the risk of acute exacerbation in patients with stable COPD. Early assessment of NRS-2002 score can predict the risk of acute exacerbation.
