YANG Zhen's Interpretation of the Wumei Pill (乌梅丸) Based on the Theory of Qi Dynamics of Ministerial Fire
10.13288/j.11-2166/r.2026.14.003
- VernacularTitle:杨震基于相火气机学说应用乌梅丸思路探赜
- Author:
Lihong ZHU
1
;
Junjie PAN
1
;
Author Information
1. Hangzhou Hospital of Traditional Chinese Medicine Affiliated to Zhejiang Chinese Medical University,Hangzhou,310007
- Publication Type:Journal Article
- Keywords:
Wumei Pill (乌梅丸);
jueyin (厥阴) disease;
ministerial fire;
qi dynamics;
experience of famous doctors;
YANG Zhen
- From:
Journal of Traditional Chinese Medicine
2026;67(14):1481-1484
- CountryChina
- Language:Chinese
-
Abstract:
Based on Professor YANG Zhen's theory of "qi dynamics of ministerial fire", this paper systematically elucidates the pathogenesis of jueyin (厥阴) disease and the clinical rationale for applying Wumei Pill (乌梅丸). Jueyin disease is characterized by dysfunction of the middle earth in regulating qi dynamics and disruption of the pivot mechanism, leading to an upward disturbance of ministerial fire and an underlying pattern of deficiency-cold of true yang, thereby forming a state of cold and heat in complexity. Wumei Pill fully exerts the synergistic effects of sour-astringency, bitter-descending, and acrid-warm medicinals, reflecting the therapeutic principle of regulating the pivot mechanism and restraining the upward rebellion of ministerial fire, with the aim of returning fire to its source and restoring the circulation of qi. Based on the four-dimensional pathological evolution of Jueyin disease, namely disorder of pivot qi harmonization, failure of ying (营)-blood nourishment and containment, loss of yin sustenance and balance, and instabi-lity of ministerial fire, the paper systematically reveals the underlying logic of Wumei Pill in treating different diseases with the same therapeutic principle. In addition, a clinical case of hemoptysis treated with modified Wumei Pill is presented, providing insights into its formulation principles and expanding its application in complex and refractory multi-system diseases.