Annual review of clinical research on lung transplantation worldwide in 2025
- VernacularTitle:2025年国内外肺移植临床研究年度盘点
- Author:
Linxi LIU
1
;
Jingchen XU
1
;
Rui YANG
1
;
Xinchen JIANG
1
;
Ting DENG
1
;
Ling ZHOU
1
;
Kaiyue YANG
1
;
Xiaohan JIN
2
;
Zhiqiang DENG
2
;
Xiangyun ZHENG
2
;
Dong TIAN
2
Author Information
- Publication Type:AcademicSummary
- Keywords: Lung transplantation; Rejection; Infection; Ischemia-reperfusion injury; Extracorporeal membrane oxygenation; Chronic lung allograft dysfunction; Donor shortage
- From: Organ Transplantation 2026;17(4):574-581
- CountryChina
- Language:Chinese
- Abstract: Lung transplantation is currently the only effective treatment for end-stage lung disease. However, the field of lung transplantation still faces numerous challenges, including donor shortage, primary graft dysfunction, rejection, infection and others. In 2025, scholars worldwide have made remarkable progress in clinical research on lung transplantation. This article systematically reviews the cutting-edge developments in clinical research on lung transplantation in 2025, focusing on the application of novel evaluation tools in donor lung screening, optimization of lung perfusion techniques, exploration of extracorporeal membrane oxygenation and robot-assisted minimally invasive surgery, as well as mechanistic research and intervention strategies for primary graft dysfunction, acute kidney injury and chronic lung allograft dysfunction. Meanwhile, hot topics such as the management of special populations, prevention and control of postoperative infections, and improvement of quality of life are summarized. This review aims to conclude the important annual research findings and provide references for the clinical practice and research development of lung transplantation in China.
