Research progress on the effects of processing on the chemical constituents and pharmacological effects of Morinda officinalis
- VernacularTitle:炮制对巴戟天化学成分及药理作用影响的研究进展
- Author:
Na BAI
1
;
Tianyi FU
1
;
Yale MA
1
;
Chen WANG
1
;
Hongwei LI
2
;
Kai LI
2
;
Le KANG
2
;
Mengyun LIU
1
Author Information
1. School of Pharmacy,Henan University of Traditional Chinese Medicine,Zhengzhou 450046,China
2. School of Pharmacy,Henan University of Traditional Chinese Medicine,Zhengzhou 450046,China;Henan Research Center for Special Processing Technology of Chinese Medicine,Zhengzhou 450046,China
- Publication Type:Journal Article
- Keywords:
Morinda officinalis;
processing;
chemical constituents;
pharmacological effects;
treating raw and cooked differently
- From:
China Pharmacy
2026;37(13):1778-1783
- CountryChina
- Language:Chinese
-
Abstract:
Morinda officinalis is one of the “Four Great Southern Medicines” and is commonly used in clinical practice to treat erectile dysfunction and nocturnal emissions caused by kidney yang deficiency, uterine cold infertility, menstrual disorders, low abdominal pain, rheumatism, and muscle and bone weakness. Based on the principle of “treating raw and cooked differently”, this article summarizes the effects of different processing methods on the chemical constituents and pharmacological effects of M. officinalis . Research has found that processing can affect the content and structure of sugars, iridoids, and anthraquinones in M. officinalis , thereby regulating its pharmacological effects such as anti-osteoporosis, immune regulation, anti-fatigue, and anti-depression. Among them, salt M. officinalis shows outstanding performance in anti-osteoporosis and enhancing immunity. Although previous studies have preliminarily elucidated the major chemical constituents of M. officinalis and their pharmacological characteristics, the dynamic transformation paths of constituents during the processing remain to be further clarified, especially the es tablishment of a quality marker system associated with the processing technology, to achieve the precision and intelligent development of the processing.