Monte Carlo simulation and optimization analysis of dose distribution in brachytherapy
10.13491/j.issn.1004-714X.2026.02.015
- VernacularTitle:后装放射治疗剂量分布的蒙特卡罗模拟与优化分析
- Author:
Yang PAN
1
;
Lin LI
1
;
Yishui CHEN
2
;
Ning ZHOU
2
;
Nini CHU
1
Author Information
1. Beijing Institute of Occupational Disease Prevention and Treatment, Beijing 100093, China.
2. Jiangxi Institute of Occupational Disease Prevention and Treatment, Nanchang 330006, China.
- Publication Type:OriginalArticles
- Keywords:
High-dose-rate brachytherapy;
Monte Carlo;
Absorbed dose rate;
Radiation protection
- From:
Chinese Journal of Radiological Health
2026;35(2):251-257
- CountryChina
- Language:Chinese
-
Abstract:
Objective To conduct Monte Carlo simulations on the microselectro-HDR192Ir radiation source, investigate dose distributions under various conditions, and provide assistance in optimizing radiotherapy plans. Methods A microselectro-HDR192Ir radiation source model was established based on the MCNP5 software. Theoretical calculation formulas were used to validate the simulation results. The dose distributions under different activities and positions were obtained through simulations using the MCNP5 transport program. By fitting the simulation data, the relationship between the safe distance for at-risk organs and treatment time was analyzed. Results As the distance from the origin increased in the X-direction, the distance required for the absorbed dose rate to decrease to half its original value increased, and the isodose lines became sparser. The shapes of the dose distribution diagrams under different activities were consistent, presenting concentric polygons and concentric circles at different distances. Under the condition of the same lethal dose, the difference in the safe distance between two organs increased with time; under different lethal dose conditions, the differences were not significant whether between similar organs or between different organs. Conclusion The Monte Carlo method can accurately describe the radiation field generated by the microselectro-HDR192Ir radioactive source during high-dose-rate brachytherapy. Quantitative analysis of the radiation field will help optimize the radiotherapy plan.
