A case report of unilateral tibia and fibula oligometastasis from prostate cancer
10.12483/j.issn.1009-8291.2026.06.016
- VernacularTitle:前列腺癌伴单侧胫腓骨寡转移1例报告
- Author:
Boye ZHOU
1
;
Zhenhu ZHOU
2
Author Information
1. Department of Graduate Studies, Shandong First Medical University, Ji'nan 250117
2. Department of Nuclear Medicine, Liaocheng Hospital Affiliated to Shandong First Medical University(Liaocheng People's Hospital), Liaocheng 252000, China
- Publication Type:Journal Article
- Keywords:
metastatic prostate cancer;
tibia and fibula;
oligometastasis
- From:
Journal of Modern Urology
2026;31(6):603-605
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the diagnosis and treatment of oligometastatic prostate cancer with unilateral tibia and fibula involvement, so as to provide reference for the management of this condition. Case Report An 85-year-old male sought medical attention for left lower extremity swelling and pain.Diagnostic workup included computed tomography (CT), magnetic resonance imaging (MRI), pathological and immunohistochemical analysis of a left tibial biopsy, prostate biopsy, and a whole-body bone scan.These investigations confirmed prostate acinar adenocarcinoma with a Gleason score of 9 (4+5).The bone scan demonstrated foci of increased radiotracer uptake in the left tibia and fibula, establishing the final diagnosis of prostate cancer with unilateral oligometastasis to these bones.Following endocrine therapy, follow-up revealed a significant decrease in prostate-specific antigen (PSA) level along with shrinkage of the primary lesion on prostate MRI. Conclusion Prostate cancer can rarely manifest with distal limb oligometastases as its initial presentation, a condition prone to misdiagnosis as osteomyelitis or other bone disorders.This possibility should be considered and promptly screened in elderly males with unexplained bone pain.
