Clinical efficacy of 450 nm blue laser vaporization enucleation of the prostate in the treatment of benign prostatic hyperplasia complicated with urinary retention
10.12483/j.issn.1009-8291.2026.04.010
- VernacularTitle:450nm蓝激光前列腺汽化剜切术治疗良性前列腺增生合并尿潴留的疗效
- Author:
Weihao CHEN
1
;
Yi WANG
1
;
Yipeng JIN
1
;
Yubo ZHAO
1
;
Xiyou WANG
1
;
Yansheng XU
1
;
Chuan ZHANG
1
;
Anlong CHEN
1
;
Changliang XIE
1
;
Zhuomin JIA
1
Author Information
1. Department of Urology, The Third Medical Center of Chinese PLA General Hospital, Beijing 100039, China
- Publication Type:Journal Article
- Keywords:
benign prostatic hyperplasia;
lower urinary tract symptom;
450 nm blue laser;
urinary retention
- From:
Journal of Modern Urology
2026;31(4):352-355
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the efficacy and safety of 450 nm blue laser vaporization enucleation of the prostate in the treatment of benign prostatic hyperplasia(BPH)complicated with urinary retention, so as to promote its clinical application. Methods A retrospective analysis was conducted on the clinical data of 60 patients with BPH and urinary retention who underwent 450 nm blue laser vaporization enucleation of the prostate in our hospital during Feb. 2023 and Apr. 2024. All patients had urinary catheters indwelt preoperatively due to urinary retention. The perioperative indicators and complications were recorded. The maximum urinary flow rate(Qmax), postvoid residual(PVR), international prostate symptom score(IPSS), and quality of life score(QoL)were compared before surgery and 3 months after surgery. Results All procedures were completed successfully without conversion to transurethral resection of the prostate(TURP). No cases of severe intraoperative bleeding or transfusion were reported. The average operation time was(60.5±21.5)min, postoperative hemoglobin reduction(3.2±0.8)g/L, catheterization time(3.1±0.4)days, and hospital stay(3.2±0.4)days. No bladder perforation or urethral injury occurred. At 3 months postoperatively, Qmax [(19.2±4.9)mL/s vs.(3.5±2.3)mL/s], PVR [(50.8±20.1)mL vs.(369.2±163.2)mL], IPSS [(9.7±0.9)vs.(21.8±3.2)], and QoL [(1.4±0.5)vs.(4.9±0.1)]were significantly improved compared with preoperative values(P＜0.001). Urinary retention occurred in 2 patients after catheter removal on postoperative day 3, which was resolved one week after re-catheterization. Conclusion The 450 nm blue laser vaporization enucleation of the prostate is a safe and effective treatment for BPH complicated with urinary retention. It can significantly improve the short-term voiding function and quality of life with a low incidence of postoperative complications, demonstrating promising potential for clinical adoption.
