Penile metastatic extramedullary plasmacytoma:a case report and literature review
10.12483/j.issn.1009-8291.2026.03.018
- VernacularTitle:阴茎转移性髓外浆细胞瘤1例并文献复习
- Author:
Zhihao WANG
1
;
Yuping ZHAO
1
;
Wanhe WU
1
;
Haidi LYU
2
;
Baihong GUO
2
Author Information
1. The First Clinical Medical College of Gansu University of Chinese Medicine, Lanzhou 730000
2. Department of Urology, Gansu Provincial People's Hospital, Lanzhou 730000, China
- Publication Type:Journal Article
- Keywords:
extramedullary plasmacytoma;
penile metastasis;
lymphoma
- From:
Journal of Modern Urology
2026;31(3):295-297
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the clinicopathological characteristics, diagnostic key points, and treatment strategies of penile metastatic extramedullary plasmacytoma(EMP). Case Report A 47-year-old male patient presented with a painless indurated nodule on the dorsal side of the penis and had a previous history of plasmacytoma in the nasal cavity and tibia. He subsequently underwent complete excision of the penile lesion. Postoperative histopathological examination confirmed the diagnosis of anaplastic plasmacytoma. Immunohistochemical analysis showed positive staining of CD138, CD38, MUM1, and CD79a, with Ki-67(+60%). Light chain restriction was also identified. No local recurrence or distant metastasis was observed during the 5-month follow-up. Conclusion Metastatic EMP of the penis is an extremely rare condition, and the diagnosis relies on pathological examinations combined with immunohistochemical analysis. Surgical resection can be an effective treatment modality for localized lesions;however, long-term follow-up is essential to monitor disease progression.
