Testicular Ewing sarcoma:a case report and literature review
10.12483/j.issn.1009-8291.2026.03.011
- VernacularTitle:睾丸尤因肉瘤1例报告并文献复习
- Author:
Kaifeng LIU
1
;
Shihao LI
1
;
Liangmeng GAO
1
;
Yuanning ZHENG
1
;
Hongwei LIU
1
Author Information
1. Laboratory of Urology and Department of Urology, The Affiliated Hospital of Guangdong Medical University, Zhanjiang 524001, China
- Publication Type:Journal Article
- Keywords:
testicle;
Ewing sarcoma;
extraosseous Ewing sarcoma;
fluorescence in situ hybridization
- From:
Journal of Modern Urology
2026;31(3):264-267
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore the clinical features, diagnosis, treatment and prognosis of testicular Ewing sarcoma(ES), so as to enhance the understanding and differential diagnosis of this disease. Methods A retrospective analysis was conducted on the clinical manifestations, auxiliary examinations and pathological findings of a case of left-sided ES treated at our hospital, supplemented by a review of relevant literature. Results A 24-year-old male patient presented with left testicular enlargement with pain. Magnetic resonance imaging suggested a neoplastic lesion, with a high likelihood of testicular germ cell tumor. A radical left orchiectomy was performed. Postoperative pathology revealed testicular ES. The patient subsequently completed 8 cycles of VDC/IE chemotherapy and showed no evidence of recurrence at 10 months of follow-up. Analysis of literature on 5 previously reported cases of testicular ES had testicular enlargement as the primary presentation. All patients underwent surgery and 4 received adjuvant therapy. Follow-up revealed 1 death at 9 months postoperatively, with no recurrence or progression seen in the remainder. Conclusion ES occurring in the testis is extremely rare.Testicular ES is a poorly differentiated small round-cell malignant tumor that primarily presents as testicular enlargement. Current treatment mainly surgical resection combined with adjuvant chemotherapy.
