Research progress of parasite-derived microRNA in Echinococcus and echinococcosis

VernacularTitle:虫源性MicroRNA在棘球蚴及棘球蚴病中的研究进展
Author: Hong-bin ZHANG ¹ ; Ning YANG ¹ ; Xiao-juan BI ¹ ; Ren-yong LIN ¹
Author Information

1. State Key Laboratory of Pathogenesis, Prevention, and Treatment of Diseases Highly Endemic to Central Asia, Clinical Medical Research Institute, The First Hospital Af-filiated with Xinjiang Medical University, Urumqi 830054, China
Publication Type:Journal Article
Keywords: Echinococcosis; MicroRNA; Cross-species regulation
From: Acta Parasitologica et Medica Entomologica Sinica 2026;33(1):75-80
CountryChina
Language:Chinese
Abstract: Echinococcosis is categorized into alveolar echinococcosis and cystic echinococcosis, a potentially fatal zoonotic disease that seriously damages the host. MicroRNA is a type of endogenous small non-coding RNA that binds specifically to the target gene mRNA sequence to promote mRNA degradation, or combines with other non-coding RNA to regulate or inhibit translation. Echinococcus-derived microRNA participates in various biological processes in the Echinococcus lifecycle and in the interaction and pathogenesis between Echinococcus and host through extracellular vesicle transport. This article reviews the research progress of parasite-derived microRNA in regulating the growth and development of echinococcosis and cross-species regulation of hosts, providing a reference for diagnosing and treating echinococcosis.