Clinical effects of traditional “mchin tang” decoction on the alcohol-induced hepatotoxicity: a randomized controlled clinical trial
- VernacularTitle:Архины шалтгаант элэгний хордлогот үрэвслийн үеийн эмнэлзүйд чинтан уламжлалт эмийн үзүүлэх нөлөө - санамсаргүй хяналттай клиник туршилт
- Author:
Bayanjargal Purevsuren
1
;
Tuul Khalzaibaast
2
;
Bold Sharav
1
Author Information
1. Sindura-med hospital, Mongolian University of Pharmaceutical Sciences, Ulaanbaatar, Mongolia
2. Deparment of Traditional Medicine, Otoch Manramba University, Ulaanbaatar, Mongolia
- Publication Type:Clinical Trial
- Keywords:
traditional medicine;
Mchin tang decoction;
alcohol induced liver disease;
a randomized controlled clinical trial
- From:
Mongolian Pharmacy and Pharmacology
2026;29(2):75-81
- CountryMongolia
- Language:Mongolian
-
Abstract:
Introduction:This study aims to elucidate the mechanism of action and therapeutic efficacy of Mchin
tang, a decoction from Chapter 59 of the “Man Ngag Lhanthab,” for treating alcohol-induced liver toxicity
in patients.
Methods:Conducted as a rigorous single-center randomized controlled trial in 2024 and 2025 at Sindura-med Hospital and Borjigon Otoch Hospital, involving 38 carefully selected alcohol-dependent patients who
provided informed consent.
Conclusion:The findings demonstrate that the Mchin tang drug group showed notable improvement in
treating liver toxicity symptoms, which may encourage healthcare professionals to consider traditional
medicine as a viable option. Compared with the Silymarin treatment group, the physical and neurological
symptoms associated with the alcohol liver disease were significantly reduced in the Mchin tang traditional
medicine treatment group, and the headache, hypertension, and numbness were also significantly reduced in the Mchin tang traditional medicine treatment group. A questionnaire clarified the differential diagnosis of headache and hypertension.
The findings suggest that traditional Mchin tang medicine can effectively reduce liver heat disease symptoms and related neurological issues, encouraging further exploration and application in clinical practice.
- Full text:2026080202191797426MPPJ-2026-29(2)-75-81.pdf