Whole-Body Phase Angle as a Marker of Cellular Health in a Workplace Lifestyle Intervention
https://doi.org/10.15605/jafes.041.S1
- Author:
Mohd Nahar Azmi Bin Mohamed
1
;
Nurul Zfarina Binti Mohd Zaid
2
Author Information
1. Wellness Unit, Faculty of Medicine, University of Malaya; Department of Sports Medicine, Faculty of Medicine, University of Malaya
2. Wellness Unit, Faculty of Medicine, University of Malaya
- Publication Type:Journal Article
- MeSH:
Workplace
- From:
Journal of the ASEAN Federation of Endocrine Societies
2026;41(S1):57-
- CountryPhilippines
- Language:English
-
Abstract:
Introduction:Phase angle (PhA) derived from bioelectrical impedance
analysis reflects cellular integrity and has emerged as a
potential marker of metabolic health. Its role in detecting
early physiological changes during lifestyle intervention
remains underexplored in workplace obesity programmes.
Methodology:This longitudinal study included 30 adults with complete
paired measurements enrolled in a 12-month workplace
lifestyle programme. Body composition was assessed
using multifrequency bioelectrical impedance analysis.
Measurements included whole-body PhA, body cell mass
(BCM), skeletal muscle index (SMI), and extracellular
water to total body water ratio. Paired comparisons and
correlation analyses were performed.
Results:Mean PhA increased modestly from 5.59 ± 0.70° to 5.67 ±
0.69°, although this did not reach statistical significance (p
= 0.17). Changes in PhA were not significantly associated
with changes in BCM (r = −0.03, p = 0.89). However, baseline
PhA demonstrated a moderate positive association with
SMI (r ≈ 0.51, p <0.01), suggesting a link between cellular
integrity and muscle status. Individual trajectories revealed
heterogeneous responses despite minimal weight change.
Conclusion:Whole-body phase angle provides insight into cellular
health beyond conventional anthropometric measures.
While short-term changes were modest, PhA may serve
as a clinically useful adjunct for monitoring physiological
response in obesity management programmes.
- Full text:2026073016460488022EP_A069.pdf