Gastrointestinal Stromal Tumour Masquerading as a Gynaecological Neoplasm
- Author:
Akmal Aizat BAKHORI
;
Mohd Nizam Md HASHIM
;
Mohan A
;
Muhammad Taqiyuddin YAHAYA
;
Noor Iman Mohd ISA
;
Faezahtul Arbaeyah HUSSAIN
- Publication Type:Case Report
- Keywords:
Stomach neoplasm;
Interstitial cells of Cajal;
KIT mutation;
CD34 antigen;
Ovarian neoplasm
- From:
Brunei International Medical Journal
2026;22():105-109
- CountryBrunei Darussalam
- Language:English
-
Abstract:
Gastrointestinal stromal tumours (GISTs) are mesenchymal tumours commonly found in the gastrointestinal tract, particularly in the stomach, but they can mimic gynaecological tumours. We report the case of a 56 -year-old postmenopausal woman who presented with a right adnexal pelvic mass. Computed tomography (CT) revealed a large, lobulated pelvic mass with liver lesions. Pan - endoscopy showed normal findings, and her tumour markers were within normal limits. Based on these findings, the gynaecological oncology team proceeded with a laparotomy and tumour debulking, diagnosing the pelvic mass as likely ovarian in origin. Intraoperatively, the mass was found to originate from the stomach and extend posteriorly to the transverse colon. An en -bloc resection with primary anastomosis was performed and histopathology confirmed a high -risk GIST. The patient made a good post -operative recovery and was scheduled for adjuvant chemotherapy at her follow -up visit. This case highlights the importance of considering GIST as a differential diagnosis in postmenopausal women presenting with an abdominopelvic mass that may mimic an ovarian tumour
