SUBACUTE MYELOPATHY FOLLOWING INTRATHECAL CHEMOTHERAPY ADMINISTRATION
- Author:
N AB MUMIN
1
;
MT RAMLI HAMID
1
;
K RAHMAT
2
;
V JAWIN
3
;
N RAMLI
2
Author Information
1. Department of Radiology, Faculty of Medicine, Universiti Teknologi MARA, Sg Buloh, Selangor, Malaysia
2. Department of Biomedical Imaging, University of Malaya, Kuala Lumpur, Malaysia.
3. Department of Paediatrics, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.
- Publication Type:Case Reports
- Keywords:
Acute lymphoblastic leukemia;
Chemotherapy-induced;
Intrathecal;
Myelopathy;
Magnetic resonance imaging
- From:
Brunei International Medical Journal
2022;18():29-33
- CountryBrunei Darussalam
- Language:English
-
Abstract:
Methotrexate and cytarabine are intrathecal chemotherapy agents for acute lymphoblastic leukaemia. We report a case of a paediatric patient with late onset CNS relapse of Pre-B acute lymphoblastic leukaemia who developed chemotherapy-induced myelopathy secondary to triple intrathecal chemotherapy (TIT) with its imaging findings. Imaging plays a role in localising abnormality within the spinal cord for diagnosis and aids clinicians to prevent further axonal damage by stopping the causative chemotherapeutic agents.
- Full text:2026072313032650783BIMJ2022-18-29-33.pdf
