SMALL CELL NEUROENDOCRINE CARCINOMA OF HYPOPHARYNX – JOURNEY TO DIAGNOSIS AND TREATMENT
- Author:
Vinota PANISELVAM
1
;
Elsie Jane ANASTASIUS
2
;
Azliana AZIZ
3
Author Information
1. Department of Otorhinolaryngology – Head and Neck Surgery Queen Elizabeth Hospi- tal, Kota Kinabalu, Sabah, Malaysia. Department of Otorhinolaryngology – Head and Neck Surgery, School of Medical Sci- ences, University Sains Malaysia, Kota Bharu, Kelantan, Malaysia.
2. Department of Otorhinolaryngology – Head and Neck Surgery Queen Elizabeth Hospi- tal, Kota Kinabalu, Sabah, Malaysia
3. Department of Otorhinolaryngology – Head and Neck Surgery, School of Medical Sci- ences, University Sains Malaysia, Kota Bharu, Kelantan, Malaysia
- Publication Type:Case Reports
- Keywords:
Chemotherapy;
Elderly;
Hypopharynx;
Neuroendocrine malignancy;
Radia- tion therapy
- From:
Brunei International Medical Journal
2023;19():8-12
- CountryBrunei Darussalam
- Language:English
-
Abstract:
Neuroendocrine tumours are rare and aggressive heterogenous histologic group of tumours with a wide spectrum of differentiation. They are divided into 3 categories according to its grade, clinical behaviours and prognosis; well-differentiated or low-grade, moderately differentiated or intermediate-grade, and poorly differentiated or high-grade based on the 2017 World Health Organisation Classification for Head and Neck Tumours. They commonly originate at larynx, with only 4% arising from the hypopharynx. Experience regarding diagnosis and treatment of hypopharyngeal NEC cancer are scarce and are mostly consisted of case studies or small case series. Here, we report a rare case of hypopharyngeal small cell type NEC malignancy and discuss the clinical manifestation, pathway to diagnosis and treatment.
- Full text:2026072214564102352BIMJ2023-19-8-12.pdf
