Serum Lactate Dehydrogenase As A Predictor Of Outcomes In Russell’s Viper Envenomation
- Author:
Aung Ye Kyaw
;
Shyh Poh Teo
- Collective Name:
- Publication Type:Journal Article
- Keywords:
acute kidney injury;
disseminated intravascular coagulation;
envenomation;
lactate dehydrogenase;
snake bites
- From:
Pacific Journal of Medical Sciences
2025;27(1):44-49
- CountryPapua New Guinea
- Language:English
-
Abstract:
Russell’s viper (Daboia russelii) envenomation is a major cause of morbidity and mortality in
Myanmar, often complicated by acute kidney injury (AKI), disseminated intravascular coagulation
(DIC), and shock. Serum lactate dehydrogenase (LDH), a marker of tissue injury and hemolysis,
shows promise as an indicator of envenomation severity. The objective of this study is to
determine the association between serum LDH levels and clinical outcomes in patients with
Russell’s viper envenomation. A hospital-based cross-sectional study was conducted at
Mandalay General Hospital, Myanmar, from January to December 2018. Patients admitted within
72 hours of confirmed Russell’s viper bite were included. Serum LDH was measured 18–72 hours
after the bite, and outcomes recorded included AKI, DIC, shock, and mortality. Statistical analysis
was performed using t-tests and one-way ANOVA, with p < 0.05 considered significant.
