Oxidative stress markers of male Wistar rats following recovery period from exposure to cannabis sativa

VernacularTitle:
Author: Amuda Oluwasola ; Lailat N Usman
Publication Type:Journal Article
Keywords: cannabis sativa; oxidative stress; dose dependent; recovery period
From: Pacific Journal of Medical Sciences 2024;25(2):65-74
CountryPapua New Guinea
Language:English
Abstract: Smoking of Cannabis sativa (Marijuana), a known psychoactive substance may result in side effect on living cells of the system. The aim of this study was to investigate the effect of Cannabis sativa (CS) on oxidative stress and the recovery period in male rats. Forty rats with mean weight of (170 g ± 1.24) were separately assigned into four groups of ten animals each. The rats in groups 1, 2, 3 and 4 received orally 1.0 ml of distilled water (control), 2.0mg, 4.0mg and 6.0mg of CS respectively for two weeks. Five animals from each group were sacrificed on the 15th day and the remaining animals were left for additional two weeks without treatment but with access to water and food before sacrifice.