Meta-analysis of the safety and efficacy of transurethral blue laser vaporization of the prostate,transurethral resection of the prostate or plasmakinetic resection of the prostate in the treatment of benign prostatic hyperplasia
10.12483/j.issn.1009-8291.2026.02.007
- VernacularTitle:经尿道前列腺蓝激光汽化术与经尿道前列腺电切术或等离子切除术治疗良性前列腺增生安全性与疗效荟萃分析
- Author:
Zhongchao HUO
1
;
Haifeng CHENG
1
;
Yongzhi HE
2
;
Lei WANG
1
;
Rui DING
1
;
Jianqi YANG
1
;
Wenting ZHAO
3
;
Zi CAI
1
;
Caiying KONG
1
;
Yiping GAO
4
Author Information
1. Department of Urology, Handan Central Hospital, Handan 056001
2. Reproductive Medicine and Genetic Center, Guangxi Zhuang Autonomous Region People's Hospital, Nanning 530000
3. Operating Room, Handan Central Hospital, Handan 056001
4. Respiratory and Critical Care Medicine Ward 1, Handan Central Hospital, Handan 056001, China
- Publication Type:Journal Article
- Keywords:
450nm semiconductor blue laser;
vaporization of the prostate;
transurethral plasmakinetic resection of prostate;
transurethral resection of the prostate;
benign prostatic hyperplasia;
lower urinary tract symptoms;
Meta-analysis
- From:
Journal of Modern Urology
2026;31(2):140-146
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the efficacy and safety of transurethral blue laser vaporization of the prostate, transurethral resection of the prostate (TURP) or plasmakinetic resection of the prostate in the treatment of benign prostatic hyperplasia (BPH). Methods The domestic and foreign clinical studies on transurethral blue laser vaporization of the prostate (observation group), TURP or plasmakinetic resection of the prostate (control group) in the treatment of BPH during Jan. 2015 and Mar. 2025 were retrieved. The data were extracted with Cochrane systematic review method. The operation time, decrease in hemoglobin, bladder irrigation time, catheter indwelling time, total complication rate, retrograde ejaculation rate and urinary incontinence rate of the two groups were compared with RevMan 5.3.0 statistical software. Results A total of 5 Chinese studies involving 491 patients (248 in the observation group and 243 in the control group) were included in the Meta-analysis. Compared with the control group, the observation group had shorter operation time [MD=-20.80, 95%CI:-26.88—-14.72, P＜0.00001], less decrease in hemoglobin [MD=-10.61, 95%CI: -20.21—-1.01, P=0.03], shorter bladder irrigation time [MD=-17.85, 95%CI: -32.62—-3.09, P=0.002], shorter catheter indwelling time [MD=-1.71, 95%CI: -2.81—- 0.62, P=0.002], lower total complication rate [OR=0.11, 95%CI: 0.06—0.21, P＜0.00001], lower retrograde ejaculation rate [OR=0.05, 95%CI: 0.02—0.16, P＜0.00001] and lower urinary incontinence rate [OR=0.24, 95%CI: 0.07—0.79, P=0.02]. There were no significant differences in other complications between the two groups (P＞0.05). The international erectile function score (IIEF-5) of the observation group was significantly higher than that of the control group [MD=1.87, 95%CI:1.16—2.57, P＜0.00001]. There were no significant differences in international prostate symptom score (IPSS), maximum urinary flow rate (Qmax) and post-voiding residual (PVR) between the two groups (P＞0.05). Conclusion All three surgical procedures can effectively improve the lower urinary tract symptoms of BPH patients. Compared with TURP or plasmakinetic resection of the prostate, transurethral blue laser vaporization of the prostate has obvious advantages in terms of perioperative recovery, reduction of total complications, urinary incontinence and retrograde ejaculation rates, and preservation of sexual function.
