Cerebral Amyloid Angiopathy (CAA) and Dementia: Case Report

Author: Haji M Ali ; Haji M Ariffin ; Muhammad H Ahmad ; Shyh P Teo
Publication Type:Journal Article
Keywords: Alzheimer’s Disease; Cerebral Amyloid Angiopathy; Cerebrovascular disorders; Dementia
From: Pacific Journal of Medical Sciences 2024;25(1):66-72
CountryPapua New Guinea
Language:English
Abstract: Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder caused by the accumulation of amyloid- beta peptides in the cerebral cortical and leptomeningeal vessels. These vascular changes can lead to micro-haemorrhages and lobar intracerebral haemorrhages. CAA becomes more prevalent as age increases. According to autopsy studies, CAA tends to be associated with Alzheimer’s disease in most cases. Currently, there is no disease-modifying treatment available. Despite that, early identification may assist clinicians to guide management requiring utilization of antiplatelet, anticoagulant, or thrombolytic drugs in patients with CAA. A case of a patient with cognitive impairment and suspected CAA is described.