Professor ZHOU Shaohua's Experience in Staged Treatment of Parkinson's Disease Based on the "Disease-Symptom-Syndrome Integration" Approach
10.13288/j.11-2166/r.2026.13.004
- VernacularTitle:周绍华“病、症、证结合”分期论治帕金森病经验
- Author:
Dinglin XU
1
;
Jiayi WANG
1
;
Liwei GE
2
;
Chunli GUO
1
;
1
Author Information
1. Xiyuan Hospital， China Academy of Chinese Medical Sciences，Beijing，100091
2. Graduate School，Beijing University of Chinese Medicine
- Publication Type:Journal Article
- Keywords:
Parkinson's disease;
experience of famous doctors;
ZHOU Shaohua
- From:
Journal of Traditional Chinese Medicine
2026;67(13):1373-1377
- CountryChina
- Language:Chinese
-
Abstract:
This paper aims to summarize Professor ZHOU Shaohua's clinical experience in treating Parkinson's disease （PD） based on the "disease-symptom-syndrome integration" approach. It is believed that kidney essence deficiency is the root cause of the disease， and phlegm-stasis accumulating toxin is the key factor for its deterioration. PD could be divided into the prodromal stage， early stage and middle-late stage. In the prodromal stage， treatment focuses on tonifying the kidney and replenishing marrow， choosing Zuogui Pill （左归丸） or Yougui Pill （右归丸） to prescribe with modifications according to accompanying non-motor symptoms such as constipation and rapid eye movement sleep behavior disorder. For the early stage， the disease is differentiated into three syndromes， liver-kidney yin deficiency with stirring wind， spleen-kidney yang deficiency， and excessive phlegm turbidity， then following the principle of "calming wind by regulating blood first"， the basic prescriptions of Dading Fengzhu Pill （大定风珠）， Yougui Pill （右归丸） and Jinshui Liujun Decoction （金水六君煎） are applied respectively， combined with Siwu Decoction （四物汤） to nourish blood and extinguish wind. For the middle-late stage， therapies of tonifying the kidney and conso-lidating original qi are combined with detoxifying and resolving turbidity， prescribing fleshy and nourishing medicinals such as deer-horn glue （Cervus nippon Temminck） and turtle shell glue （Colla Carapacis et Plastri Testudinis）， together with Huanglian Jiedu Decoction （黄连解毒汤） to clear heat， detoxify and resolve turbidity， implementing simultaneous tonification and elimination. Integrated traditional Chinese and western medicine intervention is emphasized for non-motor symptoms including orthostatic hypotension and dysphagia.
