Analysis of potentially inappropriate medication and influencing factors among the elderly in six nursing homes in Urumqi
- VernacularTitle:乌鲁木齐6家养老机构老年人潜在不适当用药情况及影响因素分析
- Author:
Qianhui LI
1
;
Jianhua WANG
2
;
Shangjie YANG
1
;
Biao WU
3
;
Lina ZHU
4
;
Dongling PENG
1
;
Hui GAO
1
;
Chunlin LUO
1
;
Zhanlei QIN
1
;
Eli GULMIRA
1
;
Ningning WANG
5
;
Aierken AIZEZIJIANG
2
;
Yubo WANG
2
Author Information
1. College of Pharmacy,Xinjiang Medical University,Urumqi 830054,China
2. Dept. of Pharmacy,the First Affiliated Hospital of Xinjiang Medical University,Urumqi 830011,China
3. Dept. of Pharmacy,the Seventh Affiliated Hospital of Xinjiang Medical University,Urumqi 830028,China
4. Dept. of Pharmacy,Xinjiang Production and Construction Corps Hospital,Urumqi 830002,China
5. Dept. of Pharmacy,Xinjiang Uygur Autonomous Region Hospital of Traditional Chinese Medicine,Urumqi 830099,China
- Publication Type:Journal Article
- Keywords:
potentially inappropriate medication;
the elderly;
nursing homes;
Chinese PIM criteria;
AGS Beers criteria;
STOPP criteria
- From:
China Pharmacy
2026;37(12):1614-1620
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the prevalence and influencing factors of potentially inappropriate medication (PIM) among the elderly in nursing homes in Urumqi based on three PIM screening tools, and to compare the applicability of different tools. METHODS A cross-sectional study design was adopted. Elderly individuals from six nursing homes in Urumqi were selected as the research subjects from May 2021 to September 2023. Demographic characteristics, disease burden and medication records of the elderly were collected. PIM screening was performed using the Chinese PIM criteria (2024 edition), the American Geriatrics Society (AGS) Beers criteria (2023 edition), and the Screening Tool of Older Person’S Prescriptions(STOPP)/Screening Tool to Alert to Right Treatment(START) (2023 edition). Fleiss’s Kappa test was used to assess the consistency among the three screening tools, and multivariate Logistic regression was used to analyze the influencing factors of PIM. RESULTS The prevalence of PIM screened by the Chinese PIM criteria was 47.4% (323/682), by the AGS Beers criteria was 43.4% (296/682), and by the STOPP criteria was 50.9% (347/682). The consistency among the three screening tools was low (Fleiss’s Kappa=0.12, P <0.001). Multivariate Logistic regression analysis showed that all three screening tools indicated that polypharmacy, aspirin use and psychotropic drug use were independent risk factors for PIM among elderly in nursing houses (all OR>1, P <0.05). CONCLUSIONS The prevalence of PIM among the elderly in nursing homes in Urumqi is relatively high. Polypharmacy, aspirin use and psychotropic drug use are common independent risk factors for PIM. There are differences in screening results among the three tools with low consistency. The Chinese PIM criteria can serve as a first-line tool for PIM screening in nursing homes.